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DOI

Using Fura-2AM microfluorimetry, it was shown for the first time that phospholipase A 2 inhibitors 4-bromophenacyl bromide and glucocorticosteroids prednisolone and dexamethasone attenuate Ca 2+ responses induced by neuroleptic trifluoperazine in macrophages. The results suggest the involvement of phospholipase A 2 and arachidonic acid metabolism cascade in the effect of trifluoperazine on intracellular Ca 2+ concentration in macrophages.

Original languageEnglish
Pages (from-to)41-43
Number of pages3
JournalDoklady Biochemistry and Biophysics
Volume478
Issue number1
DOIs
StatePublished - 2018

    Scopus subject areas

  • Chemistry(all)
  • Biophysics
  • Biochemistry

    Research areas

  • ACTIVATION, CELLS, PHENOTHIAZINES

ID: 16217496