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Natural compounds as inhibitors of thioredoxin reductase (TrxR1). / Chupakhin, E. G.; Krasavin, M. Yu.

In: Russian Chemical Bulletin, Vol. 71, No. 3, 01.03.2022, p. 443-448.

Research output: Contribution to journal › Review article › peer-review

Harvard

Chupakhin, EG & Krasavin, MY 2022, 'Natural compounds as inhibitors of thioredoxin reductase (TrxR1)', Russian Chemical Bulletin, vol. 71, no. 3, pp. 443-448. https://doi.org/10.1007/s11172-022-3431-4

APA

Chupakhin, E. G., & Krasavin, M. Y. (2022). Natural compounds as inhibitors of thioredoxin reductase (TrxR1). Russian Chemical Bulletin, 71(3), 443-448. https://doi.org/10.1007/s11172-022-3431-4

Vancouver

Chupakhin EG, Krasavin MY. Natural compounds as inhibitors of thioredoxin reductase (TrxR1). Russian Chemical Bulletin. 2022 Mar 1;71(3):443-448. https://doi.org/10.1007/s11172-022-3431-4

Author

Chupakhin, E. G. ; Krasavin, M. Yu. / Natural compounds as inhibitors of thioredoxin reductase (TrxR1). In: Russian Chemical Bulletin. 2022 ; Vol. 71, No. 3. pp. 443-448.

BibTeX

@article{46d218cfb6d74e198cb6fef676310490,
title = "Natural compounds as inhibitors of thioredoxin reductase (TrxR1)",
abstract = "Recent achievements in the area of studying biological activity of new natural compounds toward thioredoxin reductase 1 (TrxR1) are considered. The most important chemotypes of the compounds exhibiting activity toward TrxR1 were revealed. The pharmacophoric environment of the electron-deficient olefin group that possesses a chemical potential for covalent inhibiting to TrxR1 was examined.",
keywords = "natural compounds, oxidative stress, target for anticancer drugs, thioredoxin reductase",
author = "Chupakhin, {E. G.} and Krasavin, {M. Yu}",
note = "Chupakhin, E.G., Krasavin, M.Y. Natural compounds as inhibitors of thioredoxin reductase (TrxR1). Russ Chem Bull 71, 443–448 (2022). https://doi.org/10.1007/s11172-022-3431-4",
year = "2022",
month = mar,
day = "1",
doi = "10.1007/s11172-022-3431-4",
language = "English",
volume = "71",
pages = "443--448",
journal = "Russian Chemical Bulletin",
issn = "1066-5285",
publisher = "Springer Nature",
number = "3",

}

RIS

TY - JOUR

T1 - Natural compounds as inhibitors of thioredoxin reductase (TrxR1)

AU - Chupakhin, E. G.

AU - Krasavin, M. Yu

N1 - Chupakhin, E.G., Krasavin, M.Y. Natural compounds as inhibitors of thioredoxin reductase (TrxR1). Russ Chem Bull 71, 443–448 (2022). https://doi.org/10.1007/s11172-022-3431-4

PY - 2022/3/1

Y1 - 2022/3/1

N2 - Recent achievements in the area of studying biological activity of new natural compounds toward thioredoxin reductase 1 (TrxR1) are considered. The most important chemotypes of the compounds exhibiting activity toward TrxR1 were revealed. The pharmacophoric environment of the electron-deficient olefin group that possesses a chemical potential for covalent inhibiting to TrxR1 was examined.

AB - Recent achievements in the area of studying biological activity of new natural compounds toward thioredoxin reductase 1 (TrxR1) are considered. The most important chemotypes of the compounds exhibiting activity toward TrxR1 were revealed. The pharmacophoric environment of the electron-deficient olefin group that possesses a chemical potential for covalent inhibiting to TrxR1 was examined.

KW - natural compounds

KW - oxidative stress

KW - target for anticancer drugs

KW - thioredoxin reductase

UR - http://www.scopus.com/inward/record.url?scp=85128837358&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/418a3b7b-353e-349c-af57-fe9cbb784848/

U2 - 10.1007/s11172-022-3431-4

DO - 10.1007/s11172-022-3431-4

M3 - Review article

AN - SCOPUS:85128837358

VL - 71

SP - 443

EP - 448

JO - Russian Chemical Bulletin

JF - Russian Chemical Bulletin

SN - 1066-5285

IS - 3

ER -

ID: 94860734