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Markers of cellular senescence. Telomere shortening as a marker of cellular senescence. / Bernadotte, Alexandra; Mikhelson, Victor M.; Spivak, Irina M.

In: Aging, Vol. 8, No. 1, 2016, p. 3-11.

Research output: Contribution to journal › Article › peer-review

Harvard

Bernadotte, A, Mikhelson, VM & Spivak, IM 2016, 'Markers of cellular senescence. Telomere shortening as a marker of cellular senescence', Aging, vol. 8, no. 1, pp. 3-11. https://doi.org/10.18632/aging.100871

APA

Bernadotte, A., Mikhelson, V. M., & Spivak, I. M. (2016). Markers of cellular senescence. Telomere shortening as a marker of cellular senescence. Aging, 8(1), 3-11. https://doi.org/10.18632/aging.100871

Vancouver

Bernadotte A, Mikhelson VM, Spivak IM. Markers of cellular senescence. Telomere shortening as a marker of cellular senescence. Aging. 2016;8(1):3-11. https://doi.org/10.18632/aging.100871

Author

Bernadotte, Alexandra ; Mikhelson, Victor M. ; Spivak, Irina M. / Markers of cellular senescence. Telomere shortening as a marker of cellular senescence. In: Aging. 2016 ; Vol. 8, No. 1. pp. 3-11.

BibTeX

@article{6520948350094339be7f05c9c021303c,
title = "Markers of cellular senescence. Telomere shortening as a marker of cellular senescence",
abstract = "The cellular senescence definition comes to the fact of cells irreversible proliferation disability. Besides the cell cycle arrest, senescent cells go through some morphological, biochemical, and functional changes which are the signs of cellular senescence. The senescent cells (including replicative senescence and stress-induced premature senescence) of all the tissues look alike. They are metabolically active and possess the set of characteristics in vitro and in vivo, which are known as biomarkers of aging and cellular senescence. Among biomarkers of cellular senescence telomere shortening is a rather elegant frequently used biomarker. Validity of telomere shortening as a marker for cellular senescence is based on theoretical and experimental data.",
keywords = "Aging, Biomarkers, Cellular senescence, Replicative senescence, Telomere, Telomere theory",
author = "Alexandra Bernadotte and Mikhelson, {Victor M.} and Spivak, {Irina M.}",
year = "2016",
doi = "10.18632/aging.100871",
language = "English",
volume = "8",
pages = "3--11",
journal = "Aging",
issn = "1945-4589",
publisher = "Springer Nature",
number = "1",

}

RIS

TY - JOUR

T1 - Markers of cellular senescence. Telomere shortening as a marker of cellular senescence

AU - Bernadotte, Alexandra

AU - Mikhelson, Victor M.

AU - Spivak, Irina M.

PY - 2016

Y1 - 2016

N2 - The cellular senescence definition comes to the fact of cells irreversible proliferation disability. Besides the cell cycle arrest, senescent cells go through some morphological, biochemical, and functional changes which are the signs of cellular senescence. The senescent cells (including replicative senescence and stress-induced premature senescence) of all the tissues look alike. They are metabolically active and possess the set of characteristics in vitro and in vivo, which are known as biomarkers of aging and cellular senescence. Among biomarkers of cellular senescence telomere shortening is a rather elegant frequently used biomarker. Validity of telomere shortening as a marker for cellular senescence is based on theoretical and experimental data.

AB - The cellular senescence definition comes to the fact of cells irreversible proliferation disability. Besides the cell cycle arrest, senescent cells go through some morphological, biochemical, and functional changes which are the signs of cellular senescence. The senescent cells (including replicative senescence and stress-induced premature senescence) of all the tissues look alike. They are metabolically active and possess the set of characteristics in vitro and in vivo, which are known as biomarkers of aging and cellular senescence. Among biomarkers of cellular senescence telomere shortening is a rather elegant frequently used biomarker. Validity of telomere shortening as a marker for cellular senescence is based on theoretical and experimental data.

KW - Aging

KW - Biomarkers

KW - Cellular senescence

KW - Replicative senescence

KW - Telomere

KW - Telomere theory

UR - http://www.scopus.com/inward/record.url?scp=84986567947&partnerID=8YFLogxK

U2 - 10.18632/aging.100871

DO - 10.18632/aging.100871

M3 - Article

C2 - 26805432

AN - SCOPUS:84986567947

VL - 8

SP - 3

EP - 11

JO - Aging

JF - Aging

SN - 1945-4589

IS - 1

ER -

ID: 97786252