This article is dedicated to the bioethical problems in natural, medical sciences, the humanities and the higher education. The Potter bioethics as an interdisciplinary science broadens his research interests and develops new methodologies, strategies. The higher medical education has the modern alternative principles of 3R that have replaced partially some vivisection methods. This is the excellent example of the removal of special contingent inhumanity. The modern experimental biology and the teaching of medical students turn on such improvements in technique. Usage of the modern alternative principles of 3R is demonstrated with an example of education medical students at the Medical faculty of Saint-Petersburg State University.