Research output: Contribution to journal › Article › peer-review
Immunohistochemical criteria for endometrial receptivity in I/II stage endometriosis IVF-treated patients. / Krylova, Y.; Polyakova, V.; Kvetnoy, I.; Kogan, I.; Dzhemlikhanova, L.; Niauri, D.; Gzgzyan, A.; Ailamazyan, E.
In: Gynecological Endocrinology, Vol. 32, No. S2, 2016, p. 33-36.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Immunohistochemical criteria for endometrial receptivity in I/II stage endometriosis IVF-treated patients
AU - Krylova, Y.
AU - Polyakova, V.
AU - Kvetnoy, I.
AU - Kogan, I.
AU - Dzhemlikhanova, L.
AU - Niauri, D.
AU - Gzgzyan, A.
AU - Ailamazyan, E.
PY - 2016
Y1 - 2016
N2 - Background: Implantation failure of in vitro fertilization (IVF) cycles is recognized as one of key problems in contemporary reproductive medicine. Implantation itself is a multifactorial process and one can hardly expect to find a single criterion for the endometrium receptivity. Endometrium biopsy still remains the most applicable technique to diagnose abnormalities causing decrease or complete loss of endometrial receptivity. Materials and methods: We have studied 95 endometrial biopsy samples from 45 patient with I/II stage endometriosis and 40 controls from October 2014 to December 2015. Immunohistochemical analysis of key biological molecules participating in implant window formation (LIF, ER, PR, integrin, TGF-β1 and VEGF) was done to assess their predicting value for endometrial receptivity troubles. Results: The discriminant analysis demonstrated that highest information capacity was characteristic for LIF expression percent area, integrin αVβ3 both percent area and optic density in endometrial str
AB - Background: Implantation failure of in vitro fertilization (IVF) cycles is recognized as one of key problems in contemporary reproductive medicine. Implantation itself is a multifactorial process and one can hardly expect to find a single criterion for the endometrium receptivity. Endometrium biopsy still remains the most applicable technique to diagnose abnormalities causing decrease or complete loss of endometrial receptivity. Materials and methods: We have studied 95 endometrial biopsy samples from 45 patient with I/II stage endometriosis and 40 controls from October 2014 to December 2015. Immunohistochemical analysis of key biological molecules participating in implant window formation (LIF, ER, PR, integrin, TGF-β1 and VEGF) was done to assess their predicting value for endometrial receptivity troubles. Results: The discriminant analysis demonstrated that highest information capacity was characteristic for LIF expression percent area, integrin αVβ3 both percent area and optic density in endometrial str
KW - Endometrial receptivity
KW - ER
KW - implantation window
KW - integrin αVβ3
KW - IVF
KW - LIF
KW - PR
KW - TGFβ1
KW - VEGF
U2 - 10.1080/09513590.2016.1232576
DO - 10.1080/09513590.2016.1232576
M3 - Article
VL - 32
SP - 33
EP - 36
JO - Gynecological Endocrinology
JF - Gynecological Endocrinology
SN - 0951-3590
IS - S2
ER -
ID: 7596577