Research output: Contribution to journal › Article › peer-review
Hybrid systems for oral delivery of a therapeutic neuropeptide. / Sudareva, Natalia N.; Suvorova, Olga M.; Tarasenko, Irina I.; Saprykina, Natalia N.; Smirnova, Natalia V.; Petunov, Sergey G.; Radilov, Andrey S.; Timin, Alexander S.; Korzhikova-Vlakh, Evgenia G.; Vilesov, Alexander D.
In: Mendeleev Communications , Vol. 30, No. 1, 01.01.2020, p. 25-27.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Hybrid systems for oral delivery of a therapeutic neuropeptide
AU - Sudareva, Natalia N.
AU - Suvorova, Olga M.
AU - Tarasenko, Irina I.
AU - Saprykina, Natalia N.
AU - Smirnova, Natalia V.
AU - Petunov, Sergey G.
AU - Radilov, Andrey S.
AU - Timin, Alexander S.
AU - Korzhikova-Vlakh, Evgenia G.
AU - Vilesov, Alexander D.
N1 - Publisher Copyright: © 2020 Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Several hybrid systems for oral delivery of a therapeutic peptide have been prepared and investigated. Poly(l-glutamic acidco-d-phenylalanine) and silica sub-microparticles, porous CaCO3 microparticles and Lycopodium clavatum spore capsules were employed as the first level carriers included in sodium alginate granules as the second level carriers. Efficiency of the peptide encapsulation and release rate strongly depended on the nature and structure of the carriers.
AB - Several hybrid systems for oral delivery of a therapeutic peptide have been prepared and investigated. Poly(l-glutamic acidco-d-phenylalanine) and silica sub-microparticles, porous CaCO3 microparticles and Lycopodium clavatum spore capsules were employed as the first level carriers included in sodium alginate granules as the second level carriers. Efficiency of the peptide encapsulation and release rate strongly depended on the nature and structure of the carriers.
KW - alginate granules
KW - encapsulation
KW - peptide delivery systems
KW - poly(amino acids)
KW - silica and CaCO sub-microparticles
KW - sporopollenin exine capsules
KW - PROTEIN
KW - DRUG-DELIVERY
KW - ENCAPSULATION
KW - RELEASE
KW - CALCIUM-CARBONATE
KW - NANOPARTICLES
KW - PEPTIDES
KW - MICROCAPSULES
KW - silica and CaCO3 sub-microparticles
UR - http://www.scopus.com/inward/record.url?scp=85080101675&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/9d94e9d9-c0f3-3e54-b3e7-292b805181f9/
U2 - 10.1016/j.mencom.2020.01.008
DO - 10.1016/j.mencom.2020.01.008
M3 - Article
AN - SCOPUS:85080101675
VL - 30
SP - 25
EP - 27
JO - Mendeleev Communications
JF - Mendeleev Communications
SN - 0959-9436
IS - 1
ER -
ID: 70760469