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Fluorination of α-diazo-γ-lactams with the Olah reagent. / Kazantsev, Alexander; Zhukovsky, Daniil; Bubyrev, Andrey; Dar'in, Dmitry; Krasavin, Mikhail.

In: Tetrahedron Letters, Vol. 69, 152969, 13.04.2021.

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@article{59678809afa74c058a9e6de54dcf8d79,
title = "Fluorination of α-diazo-γ-lactams with the Olah reagent",
abstract = "A series of N-aryl α-fluoro-γ-lactams were successfully prepared by hydrofluorination of diazo counterparts with the Olah reagent in moderate yields. This approach was also applied to bromofluorination with N-bromosuccinimide as electrophilic bromine source.",
keywords = "Diazo compounds, N-aryl 2-pyrrolidones, The Olah reagent, α-Fluorination of carbonyl compounds, alpha-Fluorination of carbonyl compounds",
author = "Alexander Kazantsev and Daniil Zhukovsky and Andrey Bubyrev and Dmitry Dar'in and Mikhail Krasavin",
note = "Funding Information: This research was supported by the Russian Foundation for Basic Research (project grant 19-33-90016). We are grateful to the Research Centre for Magnetic Resonance and the Centre for Chemical Analysis and Materials Research of Saint Petersburg State University Research Park for the analytical data. Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = apr,
day = "13",
doi = "10.1016/j.tetlet.2021.152969",
language = "English",
volume = "69",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Fluorination of α-diazo-γ-lactams with the Olah reagent

AU - Kazantsev, Alexander

AU - Zhukovsky, Daniil

AU - Bubyrev, Andrey

AU - Dar'in, Dmitry

AU - Krasavin, Mikhail

N1 - Funding Information: This research was supported by the Russian Foundation for Basic Research (project grant 19-33-90016). We are grateful to the Research Centre for Magnetic Resonance and the Centre for Chemical Analysis and Materials Research of Saint Petersburg State University Research Park for the analytical data. Publisher Copyright: © 2021 Elsevier Ltd Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/4/13

Y1 - 2021/4/13

N2 - A series of N-aryl α-fluoro-γ-lactams were successfully prepared by hydrofluorination of diazo counterparts with the Olah reagent in moderate yields. This approach was also applied to bromofluorination with N-bromosuccinimide as electrophilic bromine source.

AB - A series of N-aryl α-fluoro-γ-lactams were successfully prepared by hydrofluorination of diazo counterparts with the Olah reagent in moderate yields. This approach was also applied to bromofluorination with N-bromosuccinimide as electrophilic bromine source.

KW - Diazo compounds

KW - N-aryl 2-pyrrolidones

KW - The Olah reagent

KW - α-Fluorination of carbonyl compounds

KW - alpha-Fluorination of carbonyl compounds

UR - http://www.scopus.com/inward/record.url?scp=85102425338&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/ee156e5a-c9db-381b-8199-dd373ef60e71/

U2 - 10.1016/j.tetlet.2021.152969

DO - 10.1016/j.tetlet.2021.152969

M3 - Article

AN - SCOPUS:85102425338

VL - 69

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

M1 - 152969

ER -

ID: 75206821