• Andrey Bzikadze
  • Alla Mikheenko
  • Павел Аркадьевич Певзнер
Recent advancements in long-read sequencing have enabled the telomere-to-telomere (complete) assembly of a human genome and are now contributing to the haplotype-resolved complete assemblies of multiple human genomes. Since the accuracy of read mapping tools deteriorates in highly-repetitive regions, there is a need to develop accurate, error-exposing (detecting potential assembly errors), and diploid-aware (distinguishing different haplotypes) tools for read mapping in complete assemblies. We describe the first accurate, error-exposing, and partially diploid-aware VerityMap tool for long-read mapping to complete assemblies.
Original languageEnglish
JournalGenome Research
DOIs
StateE-pub ahead of print - 15 Nov 2022

    Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Computer Science(all)

ID: 100330740