Standard

Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin. / Z. I. Krutetskaya, ; A. V. Melnitskaya; V. G. Antonov, ; A. D. Nozdrachev.

In: Doklady Biochemistry and Biophysics, Vol. 480, No. 1, 2018, p. 152-154.

Research output: Contribution to journal › Article › peer-review

Harvard

Z. I. Krutetskaya, , A. V. Melnitskaya, V. G. Antonov, & A. D. Nozdrachev 2018, 'Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin', Doklady Biochemistry and Biophysics, vol. 480, no. 1, pp. 152-154. https://doi.org/DOI: 10.1134/S1607672918030079

APA

Z. I. Krutetskaya, A. V. Melnitskaya, V. G. Antonov, & A. D. Nozdrachev (2018). Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin. Doklady Biochemistry and Biophysics, 480(1), 152-154. https://doi.org/DOI: 10.1134/S1607672918030079

Vancouver

Z. I. Krutetskaya , A. V. Melnitskaya, V. G. Antonov , A. D. Nozdrachev. Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin. Doklady Biochemistry and Biophysics. 2018;480(1):152-154. https://doi.org/DOI: 10.1134/S1607672918030079

Author

Z. I. Krutetskaya, ; A. V. Melnitskaya ; V. G. Antonov, ; A. D. Nozdrachev. / Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin. In: Doklady Biochemistry and Biophysics. 2018 ; Vol. 480, No. 1. pp. 152-154.

BibTeX

@article{717d3dad6f85421dae8cd0c3f5a0293b,
title = "Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin",
abstract = "Using voltage-clamp technique, the involvement of epoxygenases in immunomodulatory drug glutoximregulation of Na+ transport in frog skin was investigated. We have shown for the first time that preincubationof the frog skin with epoxygenase inhibitors econazole or proadifen almost completely inhibits thestimulatory effect of glutoxim on Na+ transport. The data suggest the involvement of the enzymes and/orproducts of epoxygenase oxidation pathway of arachidonic acid metabolism in glutoxim effect on Na+ transportin frog skin epithelium.",
keywords = "ARACHIDONIC-ACID METABOLISM, SODIUM-CHANNEL ENAC, EPITHELIUM, EXPRESSION, MICE",
author = "{Z. I. Krutetskaya} and {A. V. Melnitskaya} and {V. G. Antonov} and {A. D. Nozdrachev}",
note = "Krutetskaya, Z.I., Melnitskaya, A.V., Antonov, V.G. et al. Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin. Dokl Biochem Biophys 480, 152–154 (2018). https://doi.org/10.1134/S1607672918030079",
year = "2018",
doi = "DOI: 10.1134/S1607672918030079",
language = "English",
volume = "480",
pages = "152--154",
journal = "Doklady Biochemistry and Biophysics",
issn = "1607-6729",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "1",

}

RIS

TY - JOUR

T1 - Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin

AU - Z. I. Krutetskaya, null

AU - A. V. Melnitskaya, null

AU - V. G. Antonov, null

AU - A. D. Nozdrachev, null

N1 - Krutetskaya, Z.I., Melnitskaya, A.V., Antonov, V.G. et al. Epoxygenase Inhibitors Attenuate the Stimulatory Effect of Glutoxim on Na+ Transport in Frog Skin. Dokl Biochem Biophys 480, 152–154 (2018). https://doi.org/10.1134/S1607672918030079

PY - 2018

Y1 - 2018

N2 - Using voltage-clamp technique, the involvement of epoxygenases in immunomodulatory drug glutoximregulation of Na+ transport in frog skin was investigated. We have shown for the first time that preincubationof the frog skin with epoxygenase inhibitors econazole or proadifen almost completely inhibits thestimulatory effect of glutoxim on Na+ transport. The data suggest the involvement of the enzymes and/orproducts of epoxygenase oxidation pathway of arachidonic acid metabolism in glutoxim effect on Na+ transportin frog skin epithelium.

AB - Using voltage-clamp technique, the involvement of epoxygenases in immunomodulatory drug glutoximregulation of Na+ transport in frog skin was investigated. We have shown for the first time that preincubationof the frog skin with epoxygenase inhibitors econazole or proadifen almost completely inhibits thestimulatory effect of glutoxim on Na+ transport. The data suggest the involvement of the enzymes and/orproducts of epoxygenase oxidation pathway of arachidonic acid metabolism in glutoxim effect on Na+ transportin frog skin epithelium.

KW - ARACHIDONIC-ACID METABOLISM

KW - SODIUM-CHANNEL ENAC

KW - EPITHELIUM

KW - EXPRESSION

KW - MICE

UR - http://www.scopus.com/inward/record.url?scp=85050112372&partnerID=8YFLogxK

UR - https://www.elibrary.ru/item.asp?id=35736032

U2 - DOI: 10.1134/S1607672918030079

DO - DOI: 10.1134/S1607672918030079

M3 - Article

VL - 480

SP - 152

EP - 154

JO - Doklady Biochemistry and Biophysics

JF - Doklady Biochemistry and Biophysics

SN - 1607-6729

IS - 1

ER -

ID: 35267861