Research output: Contribution to journal › Review article › peer-review
Emotional behavior in aquatic organisms? Lessons from crayfish and zebrafish. / de Abreu, Murilo S; Maximino, Caio; Banha, Filipe; Anastácio, Pedro M; Demin, Konstantin A; Kalueff, Allan V; Soares, Marta C.
In: Journal of Neuroscience Research, Vol. 98, No. 5, 12.11.2019, p. 764-779.Research output: Contribution to journal › Review article › peer-review
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TY - JOUR
T1 - Emotional behavior in aquatic organisms?
T2 - Lessons from crayfish and zebrafish
AU - de Abreu, Murilo S
AU - Maximino, Caio
AU - Banha, Filipe
AU - Anastácio, Pedro M
AU - Demin, Konstantin A
AU - Kalueff, Allan V
AU - Soares, Marta C
N1 - © 2019 Wiley Periodicals, Inc.
PY - 2019/11/12
Y1 - 2019/11/12
N2 - Experimental animal models are a valuable tool to study the neurobiology of emotional behavior and mechanisms underlying human affective disorders. Mounting evidence suggests that various aquatic organisms, including both vertebrate (e.g., zebrafish) and invertebrate (e.g., crayfish) species, may be relevant to study animal emotional response and its deficits. Ideally, model organisms of disease should possess considerable genetic and physiological homology to mammals, display robust behavioral and physiological responses to stress, and should be sensitive to a wide range of drugs known to modulate stress and affective behaviors. Here, we summarize recent findings in the field of zebrafish- and crayfish-based tests of stress, anxiety, aggressiveness and social preference, and discuss further perspectives of using these novel model organisms in translational biological psychiatry. Outlining the remaining questions in this field, we also emphasize the need in further development and a wider use of crayfish and zebrafish models to study the pathogenesis of affective disorders.
AB - Experimental animal models are a valuable tool to study the neurobiology of emotional behavior and mechanisms underlying human affective disorders. Mounting evidence suggests that various aquatic organisms, including both vertebrate (e.g., zebrafish) and invertebrate (e.g., crayfish) species, may be relevant to study animal emotional response and its deficits. Ideally, model organisms of disease should possess considerable genetic and physiological homology to mammals, display robust behavioral and physiological responses to stress, and should be sensitive to a wide range of drugs known to modulate stress and affective behaviors. Here, we summarize recent findings in the field of zebrafish- and crayfish-based tests of stress, anxiety, aggressiveness and social preference, and discuss further perspectives of using these novel model organisms in translational biological psychiatry. Outlining the remaining questions in this field, we also emphasize the need in further development and a wider use of crayfish and zebrafish models to study the pathogenesis of affective disorders.
KW - aggressiveness
KW - anxiety
KW - crayfish
KW - social preference
KW - translational research
KW - zebrafish
KW - DANIO-RERIO
KW - AGGRESSIVE-BEHAVIOR
KW - RED SWAMP CRAYFISH
KW - ANXIETY-LIKE BEHAVIOR
KW - PROCAMBARUS-FALLAX HAGEN
KW - DOMINANCE HIERARCHY FORMATION
KW - INDIVIDUAL IDENTIFICATION
KW - INVASIVE CRAYFISH
KW - SOCIAL-INTERACTION
KW - ANIMAL-MODELS
UR - http://www.scopus.com/inward/record.url?scp=85074983977&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/emotional-behavior-aquatic-organisms-lessons-crayfish-zebrafish
U2 - 10.1002/jnr.24550
DO - 10.1002/jnr.24550
M3 - Review article
C2 - 31722127
VL - 98
SP - 764
EP - 779
JO - Journal of Neuroscience Research
JF - Journal of Neuroscience Research
SN - 0360-4012
IS - 5
ER -
ID: 48951814