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DARK Classics in Chemical Neuroscience : Kava. / Volgin, Andrey; Yang, LongEn; Amstislavskaya, Tamara; Demin, Konstantin; Wang, Dongmei; Yan, Dongni; Wang, Jingtao; Wang, Mengyao; Alpyshov, Erik; Hu, Guojun; Serikuly, Nazar; Shevyrin, Vadim; Wappler-Guzzetta, Edina; de Abreu, Murilo; Kalueff, Allan.

In: ACS Chemical Neuroscience, 2020.

Research output: Contribution to journal › Review article › peer-review

Harvard

Volgin, A, Yang, L, Amstislavskaya, T, Demin, K, Wang, D, Yan, D, Wang, J, Wang, M, Alpyshov, E, Hu, G, Serikuly, N, Shevyrin, V, Wappler-Guzzetta, E, de Abreu, M & Kalueff, A 2020, 'DARK Classics in Chemical Neuroscience: Kava', ACS Chemical Neuroscience. https://doi.org/10.1021/acschemneuro.9b00587

APA

Volgin, A., Yang, L., Amstislavskaya, T., Demin, K., Wang, D., Yan, D., Wang, J., Wang, M., Alpyshov, E., Hu, G., Serikuly, N., Shevyrin, V., Wappler-Guzzetta, E., de Abreu, M., & Kalueff, A. (2020). DARK Classics in Chemical Neuroscience: Kava. ACS Chemical Neuroscience. https://doi.org/10.1021/acschemneuro.9b00587

Vancouver

Volgin A, Yang L, Amstislavskaya T, Demin K, Wang D, Yan D et al. DARK Classics in Chemical Neuroscience: Kava. ACS Chemical Neuroscience. 2020. https://doi.org/10.1021/acschemneuro.9b00587

Author

Volgin, Andrey ; Yang, LongEn ; Amstislavskaya, Tamara ; Demin, Konstantin ; Wang, Dongmei ; Yan, Dongni ; Wang, Jingtao ; Wang, Mengyao ; Alpyshov, Erik ; Hu, Guojun ; Serikuly, Nazar ; Shevyrin, Vadim ; Wappler-Guzzetta, Edina ; de Abreu, Murilo ; Kalueff, Allan. / DARK Classics in Chemical Neuroscience : Kava. In: ACS Chemical Neuroscience. 2020.

BibTeX

@article{10b004979fe34522ab09c7b59bb30fc0,
title = "DARK Classics in Chemical Neuroscience: Kava",
abstract = "Kava (kava kava, Piper methysticum) is a common drug-containing plant in the Pacific islands. Kavalactones, its psychoactive compounds, exert potent central nervous system (CNS) action clinically and in animal models. However, the exact pharmacological profiles and mechanisms of action of kava on the brain and behavior remain poorly understood. Here, we discuss clinical and experimental data on kava psychopharmacology and summarize chemistry and synthesis of kavalactones. We also review its societal impact, drug use and abuse potential, and future perspectives on translational kava research.",
keywords = "anxiolysis, kava, kavalactones, translational drug research",
author = "Andrey Volgin and LongEn Yang and Tamara Amstislavskaya and Konstantin Demin and Dongmei Wang and Dongni Yan and Jingtao Wang and Mengyao Wang and Erik Alpyshov and Guojun Hu and Nazar Serikuly and Vadim Shevyrin and Edina Wappler-Guzzetta and {de Abreu}, Murilo and Allan Kalueff",
note = "Publisher Copyright: Copyright {\textcopyright} 2020 American Chemical Society.",
year = "2020",
doi = "10.1021/acschemneuro.9b00587",
language = "English",
journal = "ACS Chemical Neuroscience",
issn = "1948-7193",
publisher = "American Chemical Society",

}

RIS

TY - JOUR

T1 - DARK Classics in Chemical Neuroscience

T2 - Kava

AU - Volgin, Andrey

AU - Yang, LongEn

AU - Amstislavskaya, Tamara

AU - Demin, Konstantin

AU - Wang, Dongmei

AU - Yan, Dongni

AU - Wang, Jingtao

AU - Wang, Mengyao

AU - Alpyshov, Erik

AU - Hu, Guojun

AU - Serikuly, Nazar

AU - Shevyrin, Vadim

AU - Wappler-Guzzetta, Edina

AU - de Abreu, Murilo

AU - Kalueff, Allan

N1 - Publisher Copyright: Copyright © 2020 American Chemical Society.

PY - 2020

Y1 - 2020

N2 - Kava (kava kava, Piper methysticum) is a common drug-containing plant in the Pacific islands. Kavalactones, its psychoactive compounds, exert potent central nervous system (CNS) action clinically and in animal models. However, the exact pharmacological profiles and mechanisms of action of kava on the brain and behavior remain poorly understood. Here, we discuss clinical and experimental data on kava psychopharmacology and summarize chemistry and synthesis of kavalactones. We also review its societal impact, drug use and abuse potential, and future perspectives on translational kava research.

AB - Kava (kava kava, Piper methysticum) is a common drug-containing plant in the Pacific islands. Kavalactones, its psychoactive compounds, exert potent central nervous system (CNS) action clinically and in animal models. However, the exact pharmacological profiles and mechanisms of action of kava on the brain and behavior remain poorly understood. Here, we discuss clinical and experimental data on kava psychopharmacology and summarize chemistry and synthesis of kavalactones. We also review its societal impact, drug use and abuse potential, and future perspectives on translational kava research.

KW - anxiolysis

KW - kava

KW - kavalactones

KW - translational drug research

UR - http://www.scopus.com/inward/record.url?scp=85078892956&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/c84bb678-3d61-38aa-ab61-230f986363ee/

U2 - 10.1021/acschemneuro.9b00587

DO - 10.1021/acschemneuro.9b00587

M3 - Review article

C2 - 31904216

JO - ACS Chemical Neuroscience

JF - ACS Chemical Neuroscience

SN - 1948-7193

ER -

ID: 51621350