The article is based on the report made by the authors on the “International Conference on Materials, Applied Physics & Engineering (ICMAE-2018)” in Madhya Pradesh, India during 3–4th June, 2018. The aim of the research is to demonstrate the effectiveness of the synthetic method for contextual knowledge extraction from distributed information network environment for studying new trends of scientific directions. The actual objective is to reveal the trends in the corpus formation of ‘Digital Economy’ as a developing interdisciplinary research direction. In the present study, we offer the synthetic method, which combines various approaches and tools of Digital Humanities. This method is used to meet the challenges of the digital information resources selection, explication of the context knowledge and clarification of the corpus of emerging interdisciplinary scientific direction ‘Digital Economy: e-governance and smart technology’. The base of the research has proved possibility of synthetic method application to the study of trends in the development of thesauri of interdisciplinary scientific fields. The results of the research can be used to develop interdisciplinary ontology of ‘Digital Economy’.