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Conformational Active Peptides for Antiviral Therapy. / Rubel, Aleksandr A.; Egorov, Vladimir V.

In: Bioorganic Chemistry, Vol. 180, 110161, 15.09.2026.

Research output: Contribution to journal › Review article › peer-review

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BibTeX

@article{3a807fdaf9bb4470ae73012cef631cfd,
title = "Conformational Active Peptides for Antiviral Therapy",
abstract = "This review describes a class of etiotropic (direct-acting) antiviral agents that act by altering the conformation of microbial proteins and thereby disrupting their functions. Examples of peptides capable of inducing a prion-like change in viral protein conformation are considered. The potential applications of such compounds and potential challenges associated with their use are discussed.",
author = "Rubel, {Aleksandr A.} and Egorov, {Vladimir V.}",
year = "2026",
month = sep,
day = "15",
doi = "10.1016/j.bioorg.2026.110161",
language = "English",
volume = "180",
journal = "Bioorganic Chemistry",
issn = "0045-2068",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Conformational Active Peptides for Antiviral Therapy

AU - Rubel, Aleksandr A.

AU - Egorov, Vladimir V.

PY - 2026/9/15

Y1 - 2026/9/15

N2 - This review describes a class of etiotropic (direct-acting) antiviral agents that act by altering the conformation of microbial proteins and thereby disrupting their functions. Examples of peptides capable of inducing a prion-like change in viral protein conformation are considered. The potential applications of such compounds and potential challenges associated with their use are discussed.

AB - This review describes a class of etiotropic (direct-acting) antiviral agents that act by altering the conformation of microbial proteins and thereby disrupting their functions. Examples of peptides capable of inducing a prion-like change in viral protein conformation are considered. The potential applications of such compounds and potential challenges associated with their use are discussed.

UR - https://www.mendeley.com/catalogue/84389ec4-b1fd-361d-98a4-7c942c64bb2c/

U2 - 10.1016/j.bioorg.2026.110161

DO - 10.1016/j.bioorg.2026.110161

M3 - Review article

VL - 180

JO - Bioorganic Chemistry

JF - Bioorganic Chemistry

SN - 0045-2068

M1 - 110161

ER -

ID: 156009124