Research output: Contribution to journal › Article › peer-review
Cognitive impairments in depression : Neuropsychological and MRI-studies. / Wasserman, L. I.; Ivanov, M. V.; Ananjeva, N. I.; Sorokina, A. V.; Ezhova, R. V.; Ershov, B. B.; Chuykova, A. V.
In: Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova, Vol. 115, No. Special Issue 1, 2015, p. 13-19.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Cognitive impairments in depression
T2 - Neuropsychological and MRI-studies
AU - Wasserman, L. I.
AU - Ivanov, M. V.
AU - Ananjeva, N. I.
AU - Sorokina, A. V.
AU - Ezhova, R. V.
AU - Ershov, B. B.
AU - Chuykova, A. V.
N1 - Publisher Copyright: © 2015, Media Sphera. All rights reserved. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2015
Y1 - 2015
N2 - Objective. A complex neuropsychological and neuroimaging study of deep brain structures in depression with cognitive impairment. Material and methods. We studied 73 patients with endogenous depression and 86 patients with depressive syndrome in temporal epilepsy. MRI and neuropsychological methods were used to study brain structures. Results and сonclusion. Neurocognitive impairment was more severe in patients with depressive syndrome in the structure of temporal epilepsy. The differences between the patients with endogenous and organic (temporal epilepsy) affective disturbances were determined by the more marked memory and spatial-constructive impairments in patients with organic disorders. Deficit of executive functions, planning functions and cognitive organization were more typical for the patients with endogenous affective disorders. The MRI study revealed the decrease in the left hippocampus due to sclerotic processes in patients with temporal epilepsy and the increase in the right amygdale in patients with endogenous depressive disorders. The results demonstrate the significant similarity between characteristics of the cognitive profile in patients with endo- and exogenous depressions.
AB - Objective. A complex neuropsychological and neuroimaging study of deep brain structures in depression with cognitive impairment. Material and methods. We studied 73 patients with endogenous depression and 86 patients with depressive syndrome in temporal epilepsy. MRI and neuropsychological methods were used to study brain structures. Results and сonclusion. Neurocognitive impairment was more severe in patients with depressive syndrome in the structure of temporal epilepsy. The differences between the patients with endogenous and organic (temporal epilepsy) affective disturbances were determined by the more marked memory and spatial-constructive impairments in patients with organic disorders. Deficit of executive functions, planning functions and cognitive organization were more typical for the patients with endogenous affective disorders. The MRI study revealed the decrease in the left hippocampus due to sclerotic processes in patients with temporal epilepsy and the increase in the right amygdale in patients with endogenous depressive disorders. The results demonstrate the significant similarity between characteristics of the cognitive profile in patients with endo- and exogenous depressions.
KW - Depressive disorders
KW - MRI-studies
KW - Neurocognitive deficit
UR - http://www.scopus.com/inward/record.url?scp=85016124232&partnerID=8YFLogxK
U2 - 10.17116/jnevro20151151213-19
DO - 10.17116/jnevro20151151213-19
M3 - Article
AN - SCOPUS:85016124232
VL - 115
SP - 13
EP - 19
JO - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА
JF - ЖУРНАЛ НЕВРОЛОГИИ И ПСИХИАТРИИ ИМ. C.C. КОРСАКОВА
SN - 1997-7298
IS - Special Issue 1
ER -
ID: 76129905