Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
Clusterization of White Blood Cells on the Modified UPGMC Method. / Орехов, Андрей Владимирович; Шишкин, Виктор Иванович; Людкевич, Николай Сергеевич.
International Conference Dedicated to the Memory of Professor Vladimir Zubov SCP 2020: Stability and Control Processes. Springer Nature, 2022. p. 559–566.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
}
TY - GEN
T1 - Clusterization of White Blood Cells on the Modified UPGMC Method
AU - Орехов, Андрей Владимирович
AU - Шишкин, Виктор Иванович
AU - Людкевич, Николай Сергеевич
N1 - Conference code: 4
PY - 2022
Y1 - 2022
N2 - Modern methods of flow cytometry make it possible to characterize cell populations with unprecedented detail, but the traditional analysis of data using the “manual gating” method under these conditions is ineffective and unreliable. A large number of research papers have been published in recent years that describe specialized clustering algorithms for detecting and determining populations of white blood cells. However, problems related to the presence of noise and different data density remain relevant. The internal problem of cluster analysis associated with determining the preferred number of clusters, and the moment the process itself stops remains unresolved. It is proposed to use the modified UPGMC (Unweighted Pair Group Method with Centroid average) with the Markov moment of stopping the clustering process from eliminating noise and overcoming problems associated with different data density.
AB - Modern methods of flow cytometry make it possible to characterize cell populations with unprecedented detail, but the traditional analysis of data using the “manual gating” method under these conditions is ineffective and unreliable. A large number of research papers have been published in recent years that describe specialized clustering algorithms for detecting and determining populations of white blood cells. However, problems related to the presence of noise and different data density remain relevant. The internal problem of cluster analysis associated with determining the preferred number of clusters, and the moment the process itself stops remains unresolved. It is proposed to use the modified UPGMC (Unweighted Pair Group Method with Centroid average) with the Markov moment of stopping the clustering process from eliminating noise and overcoming problems associated with different data density.
UR - https://www.mendeley.com/catalogue/2370b98b-f03c-3d0e-ba07-2c4df246899e/
U2 - 10.1007/978-3-030-87966-2_62
DO - 10.1007/978-3-030-87966-2_62
M3 - Conference contribution
SP - 559
EP - 566
BT - International Conference Dedicated to the Memory of Professor Vladimir Zubov SCP 2020: Stability and Control Processes
PB - Springer Nature
T2 - Stability and Control Processes: International Conference Dedicated to the Memory of Professor Vladimir Zubov
Y2 - 5 October 2020 through 9 October 2020
ER -
ID: 95448416