Caffeine and cardiovascular diseases : critical review of current research. / Zulli, Anthony; Smith, Renee M.; Kubatka, Peter; Novak, Jan; Uehara, Yoshio; Loftus, Hayley; Qaradakhi, Tawar; Pohanka, Miroslav; Kobyliak, Nazarii; Zagatina, Angela; Klimas, Jan; Hayes, Alan; La Rocca, Giampiero; Soucek, Miroslav; Kruzliak, Peter.
In: European Journal of Nutrition, Vol. 55, No. 4, 01.06.2016, p. 1331-1343.Research output: Contribution to journal › Review article › peer-review
}
TY - JOUR
T1 - Caffeine and cardiovascular diseases
T2 - critical review of current research
AU - Zulli, Anthony
AU - Smith, Renee M.
AU - Kubatka, Peter
AU - Novak, Jan
AU - Uehara, Yoshio
AU - Loftus, Hayley
AU - Qaradakhi, Tawar
AU - Pohanka, Miroslav
AU - Kobyliak, Nazarii
AU - Zagatina, Angela
AU - Klimas, Jan
AU - Hayes, Alan
AU - La Rocca, Giampiero
AU - Soucek, Miroslav
AU - Kruzliak, Peter
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains “Which dose is safe?”, as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. This review will focus on comprehensive and critical review of the current literature and provide an avenue for further study.
AB - Caffeine is a most widely consumed physiological stimulant worldwide, which is consumed via natural sources, such as coffee and tea, and now marketed sources such as energy drinks and other dietary supplements. This wide use has led to concerns regarding the safety of caffeine and its proposed beneficial role in alertness, performance and energy expenditure and side effects in the cardiovascular system. The question remains “Which dose is safe?”, as the population does not appear to adhere to the strict guidelines listed on caffeine consumption. Studies in humans and animal models yield controversial results, which can be explained by population, type and dose of caffeine and low statistical power. This review will focus on comprehensive and critical review of the current literature and provide an avenue for further study.
KW - Caffeine
KW - Cardioprotective effects
KW - Cardiovascular diseases
KW - Clinical studies
KW - Experimental studies
KW - Pathogenesis
UR - http://www.scopus.com/inward/record.url?scp=84959332916&partnerID=8YFLogxK
U2 - 10.1007/s00394-016-1179-z
DO - 10.1007/s00394-016-1179-z
M3 - Review article
C2 - 26932503
AN - SCOPUS:84959332916
VL - 55
SP - 1331
EP - 1343
JO - European Journal of Nutrition
JF - European Journal of Nutrition
SN - 1436-6207
IS - 4
ER -
ID: 43613164