Standard

C60 adduct with L-arginine as a promising nanomaterial for treating cerebral ischemic stroke. / Kukaliia, Olegi N.; Ageev, Sergei V.; Petrov, Andrey V.; Kirik, Olga V.; Korzhevskii, Dmitrii E.; Meshcheriakov, Anatolii A.; Jakovleva, Anastasia A.; Poliakova, Liudmila S.; Novikova, Tatiana A.; Kolpakova, Maria E.; Vlasov, Timur D.; Molchanov, Oleg E.; Maistrenko, Dmitriy N.; Murin, Igor V.; Sharoyko, Vladimir V.; Semenov, Konstantin N.

In: Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 53, 102698, 01.09.2023.

Research output: Contribution to journalArticlepeer-review

Harvard

Kukaliia, ON, Ageev, SV, Petrov, AV, Kirik, OV, Korzhevskii, DE, Meshcheriakov, AA, Jakovleva, AA, Poliakova, LS, Novikova, TA, Kolpakova, ME, Vlasov, TD, Molchanov, OE, Maistrenko, DN, Murin, IV, Sharoyko, VV & Semenov, KN 2023, 'C60 adduct with L-arginine as a promising nanomaterial for treating cerebral ischemic stroke', Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 53, 102698. https://doi.org/10.1016/j.nano.2023.102698, https://doi.org/10.1016/j.nano.2023.102698

APA

Kukaliia, O. N., Ageev, S. V., Petrov, A. V., Kirik, O. V., Korzhevskii, D. E., Meshcheriakov, A. A., Jakovleva, A. A., Poliakova, L. S., Novikova, T. A., Kolpakova, M. E., Vlasov, T. D., Molchanov, O. E., Maistrenko, D. N., Murin, I. V., Sharoyko, V. V., & Semenov, K. N. (2023). C60 adduct with L-arginine as a promising nanomaterial for treating cerebral ischemic stroke. Nanomedicine: Nanotechnology, Biology, and Medicine, 53, [102698]. https://doi.org/10.1016/j.nano.2023.102698, https://doi.org/10.1016/j.nano.2023.102698

Vancouver

Kukaliia ON, Ageev SV, Petrov AV, Kirik OV, Korzhevskii DE, Meshcheriakov AA et al. C60 adduct with L-arginine as a promising nanomaterial for treating cerebral ischemic stroke. Nanomedicine: Nanotechnology, Biology, and Medicine. 2023 Sep 1;53. 102698. https://doi.org/10.1016/j.nano.2023.102698, https://doi.org/10.1016/j.nano.2023.102698

Author

Kukaliia, Olegi N. ; Ageev, Sergei V. ; Petrov, Andrey V. ; Kirik, Olga V. ; Korzhevskii, Dmitrii E. ; Meshcheriakov, Anatolii A. ; Jakovleva, Anastasia A. ; Poliakova, Liudmila S. ; Novikova, Tatiana A. ; Kolpakova, Maria E. ; Vlasov, Timur D. ; Molchanov, Oleg E. ; Maistrenko, Dmitriy N. ; Murin, Igor V. ; Sharoyko, Vladimir V. ; Semenov, Konstantin N. / C60 adduct with L-arginine as a promising nanomaterial for treating cerebral ischemic stroke. In: Nanomedicine: Nanotechnology, Biology, and Medicine. 2023 ; Vol. 53.

BibTeX

@article{d05a8ea7a59e4e4cb9ddb588c45d21a7,
title = "C60 adduct with L-arginine as a promising nanomaterial for treating cerebral ischemic stroke",
abstract = "The work aimed to investigate the biocompatibility and biological activity of the water-soluble fullerene adduct C60-Arg. It was found that the material is haemocompatible, is not cyto- and genotoxic, possesses pronounced antioxidant activity. Additionally, this paper outlines the direction of application of water-soluble fullerene adducts in the creation of neuroprotectors. It has been suggested that a putative mechanism of the protective action of the C60-Arg adduct is associated with its antioxidant properties, the ability to penetrate the blood-brain barrier, and release nitrogen monoxide as a result of the catabolism of L-arginine residues, which promote vascular relaxation. The action of the C60-Arg adduct was compared with the action of such an antioxidant as Edaravone, which is approved in Japan for the treatment of ischemic and haemorrhagic strokes.",
author = "Kukaliia, {Olegi N.} and Ageev, {Sergei V.} and Petrov, {Andrey V.} and Kirik, {Olga V.} and Korzhevskii, {Dmitrii E.} and Meshcheriakov, {Anatolii A.} and Jakovleva, {Anastasia A.} and Poliakova, {Liudmila S.} and Novikova, {Tatiana A.} and Kolpakova, {Maria E.} and Vlasov, {Timur D.} and Molchanov, {Oleg E.} and Maistrenko, {Dmitriy N.} and Murin, {Igor V.} and Sharoyko, {Vladimir V.} and Semenov, {Konstantin N.}",
year = "2023",
month = sep,
day = "1",
doi = "10.1016/j.nano.2023.102698",
language = "English",
volume = "53",
journal = "Nanomedicine: Nanotechnology, Biology, and Medicine",
issn = "1549-9634",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - C60 adduct with L-arginine as a promising nanomaterial for treating cerebral ischemic stroke

AU - Kukaliia, Olegi N.

AU - Ageev, Sergei V.

AU - Petrov, Andrey V.

AU - Kirik, Olga V.

AU - Korzhevskii, Dmitrii E.

AU - Meshcheriakov, Anatolii A.

AU - Jakovleva, Anastasia A.

AU - Poliakova, Liudmila S.

AU - Novikova, Tatiana A.

AU - Kolpakova, Maria E.

AU - Vlasov, Timur D.

AU - Molchanov, Oleg E.

AU - Maistrenko, Dmitriy N.

AU - Murin, Igor V.

AU - Sharoyko, Vladimir V.

AU - Semenov, Konstantin N.

PY - 2023/9/1

Y1 - 2023/9/1

N2 - The work aimed to investigate the biocompatibility and biological activity of the water-soluble fullerene adduct C60-Arg. It was found that the material is haemocompatible, is not cyto- and genotoxic, possesses pronounced antioxidant activity. Additionally, this paper outlines the direction of application of water-soluble fullerene adducts in the creation of neuroprotectors. It has been suggested that a putative mechanism of the protective action of the C60-Arg adduct is associated with its antioxidant properties, the ability to penetrate the blood-brain barrier, and release nitrogen monoxide as a result of the catabolism of L-arginine residues, which promote vascular relaxation. The action of the C60-Arg adduct was compared with the action of such an antioxidant as Edaravone, which is approved in Japan for the treatment of ischemic and haemorrhagic strokes.

AB - The work aimed to investigate the biocompatibility and biological activity of the water-soluble fullerene adduct C60-Arg. It was found that the material is haemocompatible, is not cyto- and genotoxic, possesses pronounced antioxidant activity. Additionally, this paper outlines the direction of application of water-soluble fullerene adducts in the creation of neuroprotectors. It has been suggested that a putative mechanism of the protective action of the C60-Arg adduct is associated with its antioxidant properties, the ability to penetrate the blood-brain barrier, and release nitrogen monoxide as a result of the catabolism of L-arginine residues, which promote vascular relaxation. The action of the C60-Arg adduct was compared with the action of such an antioxidant as Edaravone, which is approved in Japan for the treatment of ischemic and haemorrhagic strokes.

UR - https://www.mendeley.com/catalogue/94cf9477-a956-3f14-81c9-5947e66060dc/

U2 - 10.1016/j.nano.2023.102698

DO - 10.1016/j.nano.2023.102698

M3 - Article

VL - 53

JO - Nanomedicine: Nanotechnology, Biology, and Medicine

JF - Nanomedicine: Nanotechnology, Biology, and Medicine

SN - 1549-9634

M1 - 102698

ER -

ID: 113663014