Research output: Contribution to journal › Article › peer-review
Animal Models of Hemophilia B (A Review). / Кандина, Дарья Алексеевна; Ахмаров, Ильяс Идрисович; Велижанина, Мария Евгеньевна; Кириллов, Олег Андреевич; Чиринскайте, Ангелина Валерьевна; Луганская, Полина Сергеевна; Сопова, Юлия Викторовна; Леонова, Елена Ивановна.
In: Cell and Tissue Biology, Vol. 19, No. Suppl 1, 19.08.2025, p. S96–S103.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Animal Models of Hemophilia B (A Review)
AU - Кандина, Дарья Алексеевна
AU - Ахмаров, Ильяс Идрисович
AU - Велижанина, Мария Евгеньевна
AU - Кириллов, Олег Андреевич
AU - Чиринскайте, Ангелина Валерьевна
AU - Луганская, Полина Сергеевна
AU - Сопова, Юлия Викторовна
AU - Леонова, Елена Ивановна
PY - 2025/8/19
Y1 - 2025/8/19
N2 - Abstract: Animal models play a key role in biomedical research, enabling the study of disease mechanisms and the assessment of novel therapies, with precise genetic models being especially critical for rare hereditary disorders like hemophilia B. These models allow for detailed investigation of pathogenesis, evaluation of drug efficacy, and the development of innovative treatments, including gene and cell therapy. This review summarizes currently avail- able hemophilia B laboratory animal models, including spontaneously mutated and genetically engineered strains.
AB - Abstract: Animal models play a key role in biomedical research, enabling the study of disease mechanisms and the assessment of novel therapies, with precise genetic models being especially critical for rare hereditary disorders like hemophilia B. These models allow for detailed investigation of pathogenesis, evaluation of drug efficacy, and the development of innovative treatments, including gene and cell therapy. This review summarizes currently avail- able hemophilia B laboratory animal models, including spontaneously mutated and genetically engineered strains.
KW - F9 gene
KW - FIX
KW - animal models of hemophilia B
KW - hemophilia B
UR - https://www.mendeley.com/catalogue/e894b604-d48b-3131-9f73-eb57447bc9ba/
U2 - 10.1134/S1990519X25600498
DO - 10.1134/S1990519X25600498
M3 - Article
VL - 19
SP - S96–S103
JO - Cell and Tissue Biology
JF - Cell and Tissue Biology
SN - 1990-519X
IS - Suppl 1
ER -
ID: 140460486