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Allotransplantation of pancreatic islet cells and antinuclear antibodies. / Galibin, O. V.; Sherstnov, M. I.; Emanuél', V. L.; Kashchenko, V. A.; Kofman, A. V.

In: Klinicheskaia laboratornaia diagnostika, No. 3, 01.05.1996, p. 27-29.

Research output: Contribution to journal › Article › peer-review

Harvard

Galibin, OV, Sherstnov, MI, Emanuél', VL, Kashchenko, VA & Kofman, AV 1996, 'Allotransplantation of pancreatic islet cells and antinuclear antibodies', Klinicheskaia laboratornaia diagnostika, no. 3, pp. 27-29.

APA

Galibin, O. V., Sherstnov, M. I., Emanuél', V. L., Kashchenko, V. A., & Kofman, A. V. (1996). Allotransplantation of pancreatic islet cells and antinuclear antibodies. Klinicheskaia laboratornaia diagnostika, (3), 27-29.

Vancouver

Galibin OV, Sherstnov MI, Emanuél' VL, Kashchenko VA, Kofman AV. Allotransplantation of pancreatic islet cells and antinuclear antibodies. Klinicheskaia laboratornaia diagnostika. 1996 May 1;(3):27-29.

Author

Galibin, O. V. ; Sherstnov, M. I. ; Emanuél', V. L. ; Kashchenko, V. A. ; Kofman, A. V. / Allotransplantation of pancreatic islet cells and antinuclear antibodies. In: Klinicheskaia laboratornaia diagnostika. 1996 ; No. 3. pp. 27-29.

BibTeX

@article{9b7f8712820c460eb6c467702454b496,
title = "Allotransplantation of pancreatic islet cells and antinuclear antibodies",
abstract = "Antinuclear antibodies were detected and studied by indirect immunofluorescence in the sera of patients with insulin-dependent diabetes mellitus (IDDM) subjected to allotransplantation of pancreatic islet cell culture (PICT). Continuous cell lines L-41 (derivative of J-96) and HEp-2, a sensitive substrate for the detection of antinuclear antibodies, were used after enzyme treatment. Antinuclear antibodies were detected in 19.0% of diabetics in comparison with 1.5% in healthy volunteers.PICT evidently did not influence these antibodies, although a rise of hemagglutinins against sheep red cells after PICT was previously observed. The data indicate that the nuclear antigens of HEp-2 and L-41 against which antinuclear antibodies are directed are different from those found in human fetal pancreatic islet cells which have been implanted. A possible NAg maturity deficiency in fetal tissue may be another cause of their failure to affect the antinuclear antibodies.",
author = "Galibin, {O. V.} and Sherstnov, {M. I.} and Emanu{\'e}l', {V. L.} and Kashchenko, {V. A.} and Kofman, {A. V.}",
year = "1996",
month = may,
day = "1",
language = "English",
pages = "27--29",
journal = "Клиническая лабораторная диагностика",
issn = "0869-2084",
publisher = "Медицина",
number = "3",

}

RIS

TY - JOUR

T1 - Allotransplantation of pancreatic islet cells and antinuclear antibodies

AU - Galibin, O. V.

AU - Sherstnov, M. I.

AU - Emanuél', V. L.

AU - Kashchenko, V. A.

AU - Kofman, A. V.

PY - 1996/5/1

Y1 - 1996/5/1

N2 - Antinuclear antibodies were detected and studied by indirect immunofluorescence in the sera of patients with insulin-dependent diabetes mellitus (IDDM) subjected to allotransplantation of pancreatic islet cell culture (PICT). Continuous cell lines L-41 (derivative of J-96) and HEp-2, a sensitive substrate for the detection of antinuclear antibodies, were used after enzyme treatment. Antinuclear antibodies were detected in 19.0% of diabetics in comparison with 1.5% in healthy volunteers.PICT evidently did not influence these antibodies, although a rise of hemagglutinins against sheep red cells after PICT was previously observed. The data indicate that the nuclear antigens of HEp-2 and L-41 against which antinuclear antibodies are directed are different from those found in human fetal pancreatic islet cells which have been implanted. A possible NAg maturity deficiency in fetal tissue may be another cause of their failure to affect the antinuclear antibodies.

AB - Antinuclear antibodies were detected and studied by indirect immunofluorescence in the sera of patients with insulin-dependent diabetes mellitus (IDDM) subjected to allotransplantation of pancreatic islet cell culture (PICT). Continuous cell lines L-41 (derivative of J-96) and HEp-2, a sensitive substrate for the detection of antinuclear antibodies, were used after enzyme treatment. Antinuclear antibodies were detected in 19.0% of diabetics in comparison with 1.5% in healthy volunteers.PICT evidently did not influence these antibodies, although a rise of hemagglutinins against sheep red cells after PICT was previously observed. The data indicate that the nuclear antigens of HEp-2 and L-41 against which antinuclear antibodies are directed are different from those found in human fetal pancreatic islet cells which have been implanted. A possible NAg maturity deficiency in fetal tissue may be another cause of their failure to affect the antinuclear antibodies.

UR - http://www.scopus.com/inward/record.url?scp=0030140444&partnerID=8YFLogxK

M3 - Article

C2 - 8925208

AN - SCOPUS:0030140444

SP - 27

EP - 29

JO - Клиническая лабораторная диагностика

JF - Клиническая лабораторная диагностика

SN - 0869-2084

IS - 3

ER -

ID: 119469113