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A SIMPLE ROUTE TO SIDE-CHAIN FLUORINATED Β-LACTAMS FROM RING-FLUORINATED AZIRIDINES. / Konev, A.S.; Novikov, M.S.; Khlebnikov, A.F.; Tehrani, K.A.

In: Journal of Fluorine Chemistry, No. 2, 2007, p. 114-119.

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@article{537ad80b9333428999fa9fe2d4be9d17,
title = "A SIMPLE ROUTE TO SIDE-CHAIN FLUORINATED Β-LACTAMS FROM RING-FLUORINATED AZIRIDINES",
abstract = "β-Lactams bearing a Ph2CF substituent at the C(4)-atom were synthesized from N-alkyl-2-fluoro-3,3-diphenylaziridines. The transformation was realized using SbF3-mediated isomerization of the monofluoroaziridines to fluorinated aldimines, followed by Staudinger reaction with ketenes. It was shown that this reaction sequence can be performed as a one-pot procedure. {\textcopyright} 2006 Elsevier B.V. All rights reserved.",
author = "A.S. Konev and M.S. Novikov and A.F. Khlebnikov and K.A. Tehrani",
year = "2007",
language = "English",
pages = "114--119",
journal = "Journal of Fluorine Chemistry",
issn = "0022-1139",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - A SIMPLE ROUTE TO SIDE-CHAIN FLUORINATED Β-LACTAMS FROM RING-FLUORINATED AZIRIDINES

AU - Konev, A.S.

AU - Novikov, M.S.

AU - Khlebnikov, A.F.

AU - Tehrani, K.A.

PY - 2007

Y1 - 2007

N2 - β-Lactams bearing a Ph2CF substituent at the C(4)-atom were synthesized from N-alkyl-2-fluoro-3,3-diphenylaziridines. The transformation was realized using SbF3-mediated isomerization of the monofluoroaziridines to fluorinated aldimines, followed by Staudinger reaction with ketenes. It was shown that this reaction sequence can be performed as a one-pot procedure. © 2006 Elsevier B.V. All rights reserved.

AB - β-Lactams bearing a Ph2CF substituent at the C(4)-atom were synthesized from N-alkyl-2-fluoro-3,3-diphenylaziridines. The transformation was realized using SbF3-mediated isomerization of the monofluoroaziridines to fluorinated aldimines, followed by Staudinger reaction with ketenes. It was shown that this reaction sequence can be performed as a one-pot procedure. © 2006 Elsevier B.V. All rights reserved.

M3 - Article

SP - 114

EP - 119

JO - Journal of Fluorine Chemistry

JF - Journal of Fluorine Chemistry

SN - 0022-1139

IS - 2

ER -

ID: 5009826