Research output: Contribution to journal › Article › peer-review
A genomic blueprint of flax fungal parasite fusarium oxysporum f. Sp. lini. / Samsonova, Anastasia; Kanapin, Alexander; Bankin, Michael; Logachev, Anton; Gretsova, Maria; Rozhmina, Tatyana; Samsonova, Maria.
In: International Journal of Molecular Sciences, Vol. 22, No. 5, 2665, 06.03.2021, p. 1-16.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - A genomic blueprint of flax fungal parasite fusarium oxysporum f. Sp. lini
AU - Samsonova, Anastasia
AU - Kanapin, Alexander
AU - Bankin, Michael
AU - Logachev, Anton
AU - Gretsova, Maria
AU - Rozhmina, Tatyana
AU - Samsonova, Maria
N1 - Funding Information: This work was supported by RSF fund, grant 19-16-00030 to A.K., T.R., M.B. and M.S. (data processing, genome annotation, comparative proteomics, plant inoculation, plant and fungi handling, RNA extraction). A.S. and M.G. (functional genomics, genome integrity analyses) were supported by RSF fund, grant 20-14-00072. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/3/6
Y1 - 2021/3/6
N2 - Fusarium wilt of flax is an aggressive disease caused by the soil-borne fungal pathogen Fusarium oxysporum f. sp. lini. It is a challenging pathogen presenting a constant threat to flax production industry worldwide. Previously, we reported chromosome-level assemblies of 5 highly pathogenic F. oxysporum f. sp. lini strains. We sought to characterize the genomic architecture of the fungus and outline evolutionary mechanisms shaping the pathogen genome. Here, we reveal the complex multi-compartmentalized genome organization and uncover its diverse evolutionary dy-namics, which boosts genetic diversity and facilitates host adaptation. In addition, our results suggest that host of functions implicated in the life cycle of mobile genetic elements are main contribu-tors to dissimilarity between proteomes of different Fusaria. Finally, our experiments demonstrate that mobile genetics elements are expressed in planta upon infection, alluding to their role in path-ogenicity. On the whole, these results pave the way for further in-depth studies of evolutionary forces shaping the host–pathogen interaction.
AB - Fusarium wilt of flax is an aggressive disease caused by the soil-borne fungal pathogen Fusarium oxysporum f. sp. lini. It is a challenging pathogen presenting a constant threat to flax production industry worldwide. Previously, we reported chromosome-level assemblies of 5 highly pathogenic F. oxysporum f. sp. lini strains. We sought to characterize the genomic architecture of the fungus and outline evolutionary mechanisms shaping the pathogen genome. Here, we reveal the complex multi-compartmentalized genome organization and uncover its diverse evolutionary dy-namics, which boosts genetic diversity and facilitates host adaptation. In addition, our results suggest that host of functions implicated in the life cycle of mobile genetic elements are main contribu-tors to dissimilarity between proteomes of different Fusaria. Finally, our experiments demonstrate that mobile genetics elements are expressed in planta upon infection, alluding to their role in path-ogenicity. On the whole, these results pave the way for further in-depth studies of evolutionary forces shaping the host–pathogen interaction.
KW - Comparative genomics
KW - Flax
KW - Fusarium oxysporum f. sp. lini
KW - Genome architecture
KW - Genome evolution
KW - Transposable elements
KW - genome evolution
KW - lini
KW - genome architecture
KW - comparative genomics
KW - Fusarium oxysporum f
KW - flax
KW - transposable elements
KW - sp
UR - http://www.scopus.com/inward/record.url?scp=85102005776&partnerID=8YFLogxK
U2 - 10.3390/ijms22052665
DO - 10.3390/ijms22052665
M3 - Article
AN - SCOPUS:85102005776
VL - 22
SP - 1
EP - 16
JO - International Journal of Molecular Sciences
JF - International Journal of Molecular Sciences
SN - 1422-0067
IS - 5
M1 - 2665
ER -
ID: 75376188