Research output: Contribution to journal › Article › peer-review
2H-Azirines in medicinal chemistry. / Sakharov, Pavel; Novikov, Mikhail S.; Rostovskii, Nikolai V.
In: Chemistry of Heterocyclic Compounds, Vol. 57, No. 5, 01.05.2021, p. 512-521.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - 2H-Azirines in medicinal chemistry
AU - Sakharov, Pavel
AU - Novikov, Mikhail S.
AU - Rostovskii, Nikolai V.
N1 - Publisher Copyright: © 2021, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2021/5/1
Y1 - 2021/5/1
N2 - The review presents an analysis of studies published in the period 1971-2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.
AB - The review presents an analysis of studies published in the period 1971-2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.
KW - 2Н-azirines
KW - bioconjugation
KW - biological activity
KW - cycloaddition
KW - natural compounds
KW - INTERFERENCE COMPOUNDS PAINS
KW - ASYMMETRIC-SYNTHESIS
KW - 2H-azirines
KW - ACIDS
KW - AZACYCLOPROPENE
KW - LINKERS
KW - KINETIC RESOLUTION
KW - 1,3-DIPOLAR CYCLOADDITION
KW - AZIRINOMYCIN
UR - http://www.scopus.com/inward/record.url?scp=85107506793&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/c29c373b-1fc5-37e2-9e23-71fa836c740e/
U2 - 10.1007/s10593-021-02934-2
DO - 10.1007/s10593-021-02934-2
M3 - Article
AN - SCOPUS:85107506793
VL - 57
SP - 512
EP - 521
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
SN - 0009-3122
IS - 5
ER -
ID: 85010253