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2H-Azirines in medicinal chemistry. / Sakharov, Pavel; Novikov, Mikhail S.; Rostovskii, Nikolai V.

In: Chemistry of Heterocyclic Compounds, Vol. 57, No. 5, 01.05.2021, p. 512-521.

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Sakharov, Pavel ; Novikov, Mikhail S. ; Rostovskii, Nikolai V. / 2H-Azirines in medicinal chemistry. In: Chemistry of Heterocyclic Compounds. 2021 ; Vol. 57, No. 5. pp. 512-521.

BibTeX

@article{d8a8b36bc8334af78b3849cbe448e813,
title = "2H-Azirines in medicinal chemistry",
abstract = "The review presents an analysis of studies published in the period 1971-2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.",
keywords = "2Н-azirines, bioconjugation, biological activity, cycloaddition, natural compounds, INTERFERENCE COMPOUNDS PAINS, ASYMMETRIC-SYNTHESIS, 2H-azirines, ACIDS, AZACYCLOPROPENE, LINKERS, KINETIC RESOLUTION, 1,3-DIPOLAR CYCLOADDITION, AZIRINOMYCIN",
author = "Pavel Sakharov and Novikov, {Mikhail S.} and Rostovskii, {Nikolai V.}",
note = "Publisher Copyright: {\textcopyright} 2021, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2021",
month = may,
day = "1",
doi = "10.1007/s10593-021-02934-2",
language = "English",
volume = "57",
pages = "512--521",
journal = "Chemistry of Heterocyclic Compounds",
issn = "0009-3122",
publisher = "Springer Nature",
number = "5",

}

RIS

TY - JOUR

T1 - 2H-Azirines in medicinal chemistry

AU - Sakharov, Pavel

AU - Novikov, Mikhail S.

AU - Rostovskii, Nikolai V.

N1 - Publisher Copyright: © 2021, Springer Science+Business Media, LLC, part of Springer Nature.

PY - 2021/5/1

Y1 - 2021/5/1

N2 - The review presents an analysis of studies published in the period 1971-2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.

AB - The review presents an analysis of studies published in the period 1971-2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.

KW - 2Н-azirines

KW - bioconjugation

KW - biological activity

KW - cycloaddition

KW - natural compounds

KW - INTERFERENCE COMPOUNDS PAINS

KW - ASYMMETRIC-SYNTHESIS

KW - 2H-azirines

KW - ACIDS

KW - AZACYCLOPROPENE

KW - LINKERS

KW - KINETIC RESOLUTION

KW - 1,3-DIPOLAR CYCLOADDITION

KW - AZIRINOMYCIN

UR - http://www.scopus.com/inward/record.url?scp=85107506793&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/c29c373b-1fc5-37e2-9e23-71fa836c740e/

U2 - 10.1007/s10593-021-02934-2

DO - 10.1007/s10593-021-02934-2

M3 - Article

AN - SCOPUS:85107506793

VL - 57

SP - 512

EP - 521

JO - Chemistry of Heterocyclic Compounds

JF - Chemistry of Heterocyclic Compounds

SN - 0009-3122

IS - 5

ER -

ID: 85010253