Research output: Contribution to journal › Article › peer-review
“2+1B” Technetium-99m Tricarbonyl Complexes with N,N'-Bidentate Ligands and Methyl 14-Isocyano-3-methyltetradecanoate. / Мирославов, Александр Евгеньевич; Кузьменко, Пётр Михайлович; Тюпина, Маргарита Юрьевна; Сахоненкова, Анна Павловна; Сидоренко, Георгий Васильевич; Кочергина, Анастасия Романовна; Кротов, Сергей Алексеевич.
In: Radiochemistry, Vol. 66, No. 4, 01.08.2024, p. 521–529.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - “2+1B” Technetium-99m Tricarbonyl Complexes with N,N'-Bidentate Ligands and Methyl 14-Isocyano-3-methyltetradecanoate
AU - Мирославов, Александр Евгеньевич
AU - Кузьменко, Пётр Михайлович
AU - Тюпина, Маргарита Юрьевна
AU - Сахоненкова, Анна Павловна
AU - Сидоренко, Георгий Васильевич
AU - Кочергина, Анастасия Романовна
AU - Кротов, Сергей Алексеевич
PY - 2024/8/1
Y1 - 2024/8/1
N2 - A novel 12-step procedure was developed for preparing methyl 14-isocyano-3-methyltetradecanoate. “2+1B” tricarbonyl complexes [99mTc(CO)3(N^N)CN(CH2)11CH(CH3)CH2COOMe]+, where N^N = 2,2'-bipyridine(bipy) or 1,10-phenanthroline (phen), were prepared by the reaction of [99mTc(CO)3(N^N)(H2O,EtOH)]+ withmethyl 14-isocyano-3-methyltetradecanoate in aqueous ethanol. The formation of technetium-99m complexeswas confi rmed by HPLC, and the partition coeffi cient (n-octanol/water) of these complexes was measured.
AB - A novel 12-step procedure was developed for preparing methyl 14-isocyano-3-methyltetradecanoate. “2+1B” tricarbonyl complexes [99mTc(CO)3(N^N)CN(CH2)11CH(CH3)CH2COOMe]+, where N^N = 2,2'-bipyridine(bipy) or 1,10-phenanthroline (phen), were prepared by the reaction of [99mTc(CO)3(N^N)(H2O,EtOH)]+ withmethyl 14-isocyano-3-methyltetradecanoate in aqueous ethanol. The formation of technetium-99m complexeswas confi rmed by HPLC, and the partition coeffi cient (n-octanol/water) of these complexes was measured.
U2 - 10.1134/s1066362224040143
DO - 10.1134/s1066362224040143
M3 - Article
VL - 66
SP - 521
EP - 529
JO - Radiochemistry
JF - Radiochemistry
SN - 1066-3622
IS - 4
ER -
ID: 124716501