The reaction of bis(cyclohexylisocyanide) complex of Pd(II) with substituted benzo[ d ]thiazole-2-amines in the presence of triethanolamine as the base leads to the formation of deprotonated C , N -chelated carbene complexes with a structure similar to that described previously for the reaction products with unsubstituted benzo[ d ]thiazole-2-amine. The complexes were isolated in pure form and characterized using high resolution mass spectrometry, IR and NMR spectroscopy (1H, 13C{1H}, 1H-1H COSY, 1H-1H NOESY, 1H-13C HSQC, 1H-13C HMBC). The resulting complexes exhibit moderate antibacterial activity against sensitive strains of gram-negative bacteria E. coli (C600) and P. fluorescens (P218), gram-positive bacteria S. aureus (ATCC-25923) and B. subtillis (VKM B3142D), as well as fungi C. albicans (VKPGU-401/885-653).