DOI

The issue of mechanisms and clinical significance of nephroprotective action of sodium-glucose cotransporter 2 (SGLT2) inhibitors is dealt with. Discussed are the manifestations related to the following effects of the members of this pharmacological group: their influence on glomerular filtration rate, glycaemia, diuresis, ketogenesis and other factors. The results of recent experimental and clinical studies revealing particular aspects of nephroprotective action of SGLT 2 inhibitors in type 2 diabetes mellitus and other pathological conditions are analyzed.
Translated title of the contributionMECHANISMS AND CLINICAL SIGNIFICANCE OF NEPHROPROTECTIVE ACTION OF SODIUM-GLUCOSE COTRANSPORTER 2 INHIBITORS
Original languageRussian
Pages (from-to)4-9
JournalJUVENIS SCIENTIA
Issue number1
DOIs
StatePublished - 2019

    Research areas

  • chronic kidney disease, diabetes mellitus, diabetic nephropathy, Nephroprotection, oral hypoglycemic agents, SGLT2 inhibitors, диабетическая нефропатия, ингибиторы SGLT2, ингибиторы натрий-глюкозного котранспортёра 2 типа, нефропротекция, пероральные сахароснижающие препараты, сахарный диабет, хроническая болезнь почек

ID: 78376426