Hybrid vascular surgery represents a promising approach to treating occlusive atherosclerosis, combining endovascular and open surgical methods. This review examines the evolution and definition of hybrid interventions, phenotypic features of multifocal lower extremity arterial disease, outcomes from major trials, contemporary surgical treatment approaches, and prospects for novel interventions, as well as potential complications and their management. © Коллектив авторов, 2026, Content is licensed under a Creative Commons Attribution 4.0 License. http://creativecommons.org/licenses/by/4.0/