TY - JOUR

T1 - Варианты хирургического доступа и другие факторы, влияющие на ближайшие и отдаленные результаты бронхопластических лобэктомий при центральном раке легкого

AU - Жемчугова-Зеленова, Ольга Александровна

AU - Атюков, Михаил Александрович

AU - Петров, Андрей Сергеевич

AU - Земцова, Ирина Юрьевна

AU - Передерий, Владислав Евгеньевич

AU - Зинченко, Евгений Игоревич

AU - Пищик, Вадим Григорьевич

AU - Яблонский, Петр Казимирович

PY - 2026/8/12

Y1 - 2026/8/12

N2 - Objective. To improve the treatment outcomes of patients with central lung cancer by optimizing surgical approach. Material and methods. This retrospective multicenter study included 63 patients with I—III stage of central NSCLC who underwent sleeve lobectomy from May 2014 to April 2024 at three thoracic surgery centers in St. Petersburg. Results. The frequency of postoperative complications in I—II stage of central non-small cell lung cancer was 33.3% in the group of videothoracoscopic sleeve resections versus 61.1% in thoracotomy group (p=0.018). The overall 5-year survival rate was 61% in the thoracotomy group versus 90% in the videothoracoscopy group(p=0.046). Risk factors for the development of postoperative complications after sleeve lobectomies included thoracotomy (p=0.003), high body mass index (p=0.043), advanced stage of the tumor (p=0.002), and lack of covering of the bronchial anastomosis with flap (p=0.032). Independent unfavorable prognostic factors of long-term survival in patients after sleeve lobectomy include high body mass index (p=0.003), smoking history (p=0.009), intraoperative blood transfusion (p=0.036), and conversion of thoracoscopic access to thoracotomy (p=0.007). Conclusion. Videothoracoscopic sleeve lobectomies are associated with less postoperative complications in patients with I—II stages of central NSCLC, which allows to reliably reduce the incidence of postoperative complications and ensure good long-term treatment results. Several risk factors of complicated postoperative period and poor long-term survival were identified by multivariate analysis.

AB - Objective. To improve the treatment outcomes of patients with central lung cancer by optimizing surgical approach. Material and methods. This retrospective multicenter study included 63 patients with I—III stage of central NSCLC who underwent sleeve lobectomy from May 2014 to April 2024 at three thoracic surgery centers in St. Petersburg. Results. The frequency of postoperative complications in I—II stage of central non-small cell lung cancer was 33.3% in the group of videothoracoscopic sleeve resections versus 61.1% in thoracotomy group (p=0.018). The overall 5-year survival rate was 61% in the thoracotomy group versus 90% in the videothoracoscopy group(p=0.046). Risk factors for the development of postoperative complications after sleeve lobectomies included thoracotomy (p=0.003), high body mass index (p=0.043), advanced stage of the tumor (p=0.002), and lack of covering of the bronchial anastomosis with flap (p=0.032). Independent unfavorable prognostic factors of long-term survival in patients after sleeve lobectomy include high body mass index (p=0.003), smoking history (p=0.009), intraoperative blood transfusion (p=0.036), and conversion of thoracoscopic access to thoracotomy (p=0.007). Conclusion. Videothoracoscopic sleeve lobectomies are associated with less postoperative complications in patients with I—II stages of central NSCLC, which allows to reliably reduce the incidence of postoperative complications and ensure good long-term treatment results. Several risk factors of complicated postoperative period and poor long-term survival were identified by multivariate analysis.

KW - VATS

KW - central lung cancer

KW - prognostic factors

KW - sleeve lobectomy

UR - https://www.mendeley.com/catalogue/d653a682-cf32-318f-a8b3-bb3a03c64bc9/

U2 - 10.17116/endoskop2026320415

DO - 10.17116/endoskop2026320415

M3 - статья

VL - 32

SP - 5

EP - 14

JO - Endoscopic Surgery

JF - Endoscopic Surgery

SN - 1025-7209

IS - 4

ER -