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Математическое моделирование процессов формирования локомоторных паттернов при эпидуральной стимуляции спинного мозга с учетом периферической обратной связи. / Bogacheva, I. N.; Kucher, V. I.; Shcherbakova, N. A.; Musienko, P. E.; Gerasimenko, Yu P.

In: Биофизика, Vol. 50, No. 6, 2005, p. 1125-1130.

Research output: Contribution to journal › Article › peer-review

Harvard

Bogacheva, IN, Kucher, VI, Shcherbakova, NA, Musienko, PE & Gerasimenko, YP 2005, 'Математическое моделирование процессов формирования локомоторных паттернов при эпидуральной стимуляции спинного мозга с учетом периферической обратной связи', Биофизика, vol. 50, no. 6, pp. 1125-1130.

APA

Bogacheva, I. N., Kucher, V. I., Shcherbakova, N. A., Musienko, P. E., & Gerasimenko, Y. P. (2005). Математическое моделирование процессов формирования локомоторных паттернов при эпидуральной стимуляции спинного мозга с учетом периферической обратной связи. Биофизика, 50(6), 1125-1130.

Vancouver

Bogacheva IN, Kucher VI, Shcherbakova NA, Musienko PE, Gerasimenko YP. Математическое моделирование процессов формирования локомоторных паттернов при эпидуральной стимуляции спинного мозга с учетом периферической обратной связи. Биофизика. 2005;50(6):1125-1130.

Author

Bogacheva, I. N. ; Kucher, V. I. ; Shcherbakova, N. A. ; Musienko, P. E. ; Gerasimenko, Yu P. / Математическое моделирование процессов формирования локомоторных паттернов при эпидуральной стимуляции спинного мозга с учетом периферической обратной связи. In: Биофизика. 2005 ; Vol. 50, No. 6. pp. 1125-1130.

BibTeX

@article{b960d8be8bb8443b8c65780fe0257305,
title = "Математическое моделирование процессов формирования локомоторных паттернов при эпидуральной стимуляции спинного мозга с учетом периферической обратной связи",
abstract = "A mathematical model has been used to study the spinal mechanisms of the formation of locomotor patterns involving afferent feedback from limbs. Changes in the electromyographic activity of hip and ankle muscles have been recorded in experiments on electric epidural stimulation of lumbar segments of the spinal cord of mesencephalic cats. These changes fit a nonlinear dynamic model based on Van der Pol's equation with a compelling term. The conditions of the appearance of the self-sustained oscillation mode depending on the parameters of external stimulation have been analyzed. A modified equation is proposed with the role of afferent feedback and the delay between the start of stimulation and the muscle response taken into account. The mathematical model has been demonstrated to fit experimental data. Therefore, it can be used to describe the mechanism of the generation of the patterns observed and to choose optimal conditions of the epidural stimulation of the spinal cord for inducing locomotion.",
keywords = "Epidural spinal cord stimulation, Locomotor pattern, Mesencephalic cat, Nonlinear dynamic model, Peripheral feedback",
author = "Bogacheva, {I. N.} and Kucher, {V. I.} and Shcherbakova, {N. A.} and Musienko, {P. E.} and Gerasimenko, {Yu P.}",
year = "2005",
language = "русский",
volume = "50",
pages = "1125--1130",
journal = "БИОФИЗИКА",
issn = "0006-3029",
publisher = "Издательство {"}Наука{"}",
number = "6",

}

RIS

TY - JOUR

T1 - Математическое моделирование процессов формирования локомоторных паттернов при эпидуральной стимуляции спинного мозга с учетом периферической обратной связи

AU - Bogacheva, I. N.

AU - Kucher, V. I.

AU - Shcherbakova, N. A.

AU - Musienko, P. E.

AU - Gerasimenko, Yu P.

PY - 2005

Y1 - 2005

N2 - A mathematical model has been used to study the spinal mechanisms of the formation of locomotor patterns involving afferent feedback from limbs. Changes in the electromyographic activity of hip and ankle muscles have been recorded in experiments on electric epidural stimulation of lumbar segments of the spinal cord of mesencephalic cats. These changes fit a nonlinear dynamic model based on Van der Pol's equation with a compelling term. The conditions of the appearance of the self-sustained oscillation mode depending on the parameters of external stimulation have been analyzed. A modified equation is proposed with the role of afferent feedback and the delay between the start of stimulation and the muscle response taken into account. The mathematical model has been demonstrated to fit experimental data. Therefore, it can be used to describe the mechanism of the generation of the patterns observed and to choose optimal conditions of the epidural stimulation of the spinal cord for inducing locomotion.

AB - A mathematical model has been used to study the spinal mechanisms of the formation of locomotor patterns involving afferent feedback from limbs. Changes in the electromyographic activity of hip and ankle muscles have been recorded in experiments on electric epidural stimulation of lumbar segments of the spinal cord of mesencephalic cats. These changes fit a nonlinear dynamic model based on Van der Pol's equation with a compelling term. The conditions of the appearance of the self-sustained oscillation mode depending on the parameters of external stimulation have been analyzed. A modified equation is proposed with the role of afferent feedback and the delay between the start of stimulation and the muscle response taken into account. The mathematical model has been demonstrated to fit experimental data. Therefore, it can be used to describe the mechanism of the generation of the patterns observed and to choose optimal conditions of the epidural stimulation of the spinal cord for inducing locomotion.

KW - Epidural spinal cord stimulation

KW - Locomotor pattern

KW - Mesencephalic cat

KW - Nonlinear dynamic model

KW - Peripheral feedback

UR - http://www.scopus.com/inward/record.url?scp=33750338534&partnerID=8YFLogxK

M3 - статья

AN - SCOPUS:33750338534

VL - 50

SP - 1125

EP - 1130

JO - БИОФИЗИКА

JF - БИОФИЗИКА

SN - 0006-3029

IS - 6

ER -

ID: 92592549