In order to study the change in the morphometric parameters of projection triangles of the facial skull during tooth loss in adult patient, 185 categorized skulls were studied from the craniological collection of the Museum of the Department of Normal Anatomy of the Military Medical Academy. The skulls belonged to adults aged from 22 to 75 years and were separated into two groups - with complete set of teeth and complete absence of teeth on the upper jaw (100 and 85 skulls respectively). Based on standard points, the following projection triangles were developed: lateral front triangle, anterior maxillary triangle, lateral maxillary triangle, lateral infratemporal triangle. It was established that the morphometric characteristics of the proposed projection triangles of the facial skull and infratemporal fossa reliably change with tooth loss. In this case, only those sides that pass through the points located on the alveolar process of the upper jaw change. It is proved that the sides drawn through the alveolar point and the most lateral and posterior points on the alveolar process are most affected. The selection of the proposed projection triangles and the study of their features depending on the degree of preservation of the upper dentition is important for planning and anatomical justification of surgical access on the structures of the middle zone of the face.