The article is devoted to the safe use of medical devices in medical practice. The rapid development of new medical technologies in not only improves treatment outcomes, but also leads to an increased risk to the life and health of patients and medical professionals. An analysis of regulatory regulation and the implementation of state control over circulation of medical devices was carried out. It is shown that in recent years, the requirements have not only increased in volume, but also become more stringent. State control has also been strengthened. A control procurement mechanism and monitoring of the movement of medical products are being introduced. One of the main elements of safety in the use of medical devices is the removal from places of storage and use of unregistered, falsified, poor-quality medical devices. It has been established that over the past 5 years, the number of reports of Federal Service for Surveillance in Healthcare (Roszdravnadzor) about medical products in circulation illegally has increased significantly. At the same time, the growth rate is declining. As a subject of medical products circulation, a medical organization should monitor the safety and quality of medical devices, prevent the use of medical devices in circulation illegally, including using information on the website of Roszdravnadzor. Given the peculiarities of the introduction of monitoring of the movement of medical products for military healthcare, updating information remains an extremely relevant area. The probability of using a poor-quality, dangerous medical product is high for medical organizations of any type and profile. Medical organizations performing laboratory research should pay special attention to the medical products used.