The objective is to study the development and structure of the morpho-functional complex of internal vertebral venous plexus in the system of the ontogenetic relationship of the spinal cord - the spinal canal. The study was conducted on 95 preparations of the vertebral column of embryos, fetuses, infants, young adults (I-II period of mature and senile ages), grouped in accordance with the age periodization. The process of study of cadaveric material consisted of 4 series: 1 - the isolation of the spinal column, the injection of its venous structures and corrosion; 2 - stereolithography; 3 - decalcification, the production of histological sections; 4 - macro-microscopic dissection of Pirogovsky sections and morphometry. The digital indicators were combined into time series, which were analyzed in terms of growth rate (TR). The results of measurements were processed by the conventional method of variation statistics. The stages of formation of the epidural venous depending on the development processes of the spinal cord and spinal column were studied. An irregularity of growth of the internal vertebral venous plexus in the postnatal ontogeny revealed a wide range of anatomy patterns. The difference in cross sectional area of epidural veins at various levels of the spine in postnatal ontogenesis were shown. The relationship of cross-sectional areas of the internal vertebral venous plexus and the vertebral canal in newborns, teenagers and adults were investigated. It is proved that the final formation of these tangles occur only at the beginning of the Ist period of maturity. The new approaches to the understanding of ontogenetic patterns of development, formation and structure of the internal vertebral venous system in system of morphogenetic relations: the spinal cord -the Dura - the spinal canal were developed. It has been established that the internal vertebral venous plexuses have close ontogenetic relationships in the morpho-functional complex (spinal cord - spinal cord membranes - spinal column), and perform drainage, protective, thermoregulatory functions and provide interconnection with the other extravertebral veins.