Research output: Contribution to journal › Article › peer-review
ТОЛЩИНА КОМПЛЕКСА ИНТИМА-МЕДИА СОННЫХ АРТЕРИЙ И С-РЕАКТИВНЫЙ БЕЛОК У ПАЦИЕНТОВ С АБДОМИНАЛЬНЫМ ОЖИРЕНИЕМ. / Belyaeva, O. D.; Berezina, A. V.; Bazhenova, E. A.; Mandal, V.; Ananyeva, N. I.; Berkovich, O. A.; Baranova, E. I.; Shlyakhto, E. V.
In: КАРДИОВАСКУЛЯРНАЯ ТЕРАПИЯ И ПРОФИЛАКТИКА, Vol. 8, No. 4, 2009, p. 33-38.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - ТОЛЩИНА КОМПЛЕКСА ИНТИМА-МЕДИА СОННЫХ АРТЕРИЙ И С-РЕАКТИВНЫЙ БЕЛОК У ПАЦИЕНТОВ С АБДОМИНАЛЬНЫМ ОЖИРЕНИЕМ
AU - Belyaeva, O. D.
AU - Berezina, A. V.
AU - Bazhenova, E. A.
AU - Mandal, V.
AU - Ananyeva, N. I.
AU - Berkovich, O. A.
AU - Baranova, E. I.
AU - Shlyakhto, E. V.
PY - 2009
Y1 - 2009
N2 - Aim. To assess atherosclerosis severity by duplex ultrasound of common carotid arteries (CCA), as well as C-reactive protein (CRP) levels, in 30-55-year-old patients with abdominal obesity (AO).Material and methods. The study included 203 patients (mean age 45,9 +/- 0,5 years) - 152 women (mean age 45,9 +/- 0,8 years) and 51 men (mean age 44,4 +/- 1,5 years) with AO (waist circumference, WC, >= 80 cm in women, >= 94 cm in men). In total, 36,5% were overweight (body mass index, BMI, 28,0 +/- 0,2 kg/m(2)), and 63,5% were obese (BMI 35,1 +/- 0,5 kg/m(2)). All participants underwent duplex CA ultrasound (ALOKA SSD-3500, Japan); CRP level was measured by quantitative turbidimetry.Results. In AO patients, early CA atherosclerosis and increased CRP level were observed. Atherosclerotic plaques in CCA and/or internal CA were found in 39,8%. CCA intima-media thickness (IMT) correlated with WC and insulin level. CRP concentration positively correlated with IMT insulin level, WC, BMI, and negatively correlated with high-density lipoprotein cholesterol.Conclusion. In AO patients aged over 30 years, duplex CCA ultrasound should be recommended for early atherosclerosis diagnostics.
AB - Aim. To assess atherosclerosis severity by duplex ultrasound of common carotid arteries (CCA), as well as C-reactive protein (CRP) levels, in 30-55-year-old patients with abdominal obesity (AO).Material and methods. The study included 203 patients (mean age 45,9 +/- 0,5 years) - 152 women (mean age 45,9 +/- 0,8 years) and 51 men (mean age 44,4 +/- 1,5 years) with AO (waist circumference, WC, >= 80 cm in women, >= 94 cm in men). In total, 36,5% were overweight (body mass index, BMI, 28,0 +/- 0,2 kg/m(2)), and 63,5% were obese (BMI 35,1 +/- 0,5 kg/m(2)). All participants underwent duplex CA ultrasound (ALOKA SSD-3500, Japan); CRP level was measured by quantitative turbidimetry.Results. In AO patients, early CA atherosclerosis and increased CRP level were observed. Atherosclerotic plaques in CCA and/or internal CA were found in 39,8%. CCA intima-media thickness (IMT) correlated with WC and insulin level. CRP concentration positively correlated with IMT insulin level, WC, BMI, and negatively correlated with high-density lipoprotein cholesterol.Conclusion. In AO patients aged over 30 years, duplex CCA ultrasound should be recommended for early atherosclerosis diagnostics.
KW - Abdominal obesity
KW - intima-media thickness
KW - C-reactive protein
KW - HEART-DISEASE MORTALITY
KW - ARTERY WALL THICKNESS
KW - CARDIOVASCULAR-DISEASE
KW - MYOCARDIAL-INFARCTION
KW - METABOLIC SYNDROME
KW - RISK-FACTORS
KW - INSULIN-RESISTANCE
KW - BODY-COMPOSITION
KW - FOLLOW-UP
KW - ATHEROSCLEROSIS
UR - https://www.elibrary.ru/item.asp?id=13008826
M3 - статья
VL - 8
SP - 33
EP - 38
JO - КАРДИОВАСКУЛЯРНАЯ ТЕРАПИЯ И ПРОФИЛАКТИКА
JF - КАРДИОВАСКУЛЯРНАЯ ТЕРАПИЯ И ПРОФИЛАКТИКА
SN - 1728-8800
IS - 4
ER -
ID: 88775292