This article is representing a review of literature concerning complications of fetoscopic laser coagulation of the anastomoses of placenta in twin to twin transfusion syndrome (TTTS) The most effective method of treatment of the twin to twin transfusion syndrome is fetoscopic laser coagulation of placental anastomoses, that have been confirmed by randomized trials studies and systematic reviews. Despite on great progress in reducing of neonatal mortality and morbidity the intraoperative and postoperative neonatal and mother’s risks are still too high. Premature rupture of membranes, chorionamnionitis separation, septostomy, recurrence TTTS, iatrogenic syndrome of anaemiapolycythemia, intrauterine single fetal death and «mirror» Ballantyne’s syndrome are the main complications of fetoscopic laser coagulation surgery. The frequency of complications, risk factors, clinical manifestations and ways of treatment have been carefully discussed in this article. In case of wide range of complications after fetoscopic laser coagulation the patients are supposed to be supervised in special perinatal centers. The relevant reducing of prematurity delivery rate is the one of the leading factors that influenced for the further good neonatal prognosis. Only multidisciplinary approach allowed to provide good outcome for mother and twin.