Research output: Contribution to journal › Article › peer-review
ЭКСПЕРИМЕНТАЛЬНОЕ ОБОСНОВАНИЕ ЭНДОТЕЛИОПРОТЕКТИВНОГО ЭФФЕКТА ИММУНОГЛОБУЛИНОВ ДЛЯ ВНУТРИВЕННОГО ВВЕДЕНИЯ ПРИ АКУШЕРСКОЙ ПАТОЛОГИИ. / Чепанов, Сергей Владимирович; Соколов, Дмитрий Игоревич; Шляхтенко, Татьяна Николаевна; Капустин, Роман Викторович; Окорокова, Лариса Сергеевна; Белякова, Ксения Львовна; Сельков, Сергей Алексеевич.
In: Akusherstvo i Ginekologiya (Russian Federation), No. 5, 2016, p. 82-88.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - ЭКСПЕРИМЕНТАЛЬНОЕ ОБОСНОВАНИЕ ЭНДОТЕЛИОПРОТЕКТИВНОГО ЭФФЕКТА ИММУНОГЛОБУЛИНОВ ДЛЯ ВНУТРИВЕННОГО ВВЕДЕНИЯ ПРИ АКУШЕРСКОЙ ПАТОЛОГИИ
AU - Чепанов, Сергей Владимирович
AU - Соколов, Дмитрий Игоревич
AU - Шляхтенко, Татьяна Николаевна
AU - Капустин, Роман Викторович
AU - Окорокова, Лариса Сергеевна
AU - Белякова, Ксения Львовна
AU - Сельков, Сергей Алексеевич
PY - 2016
Y1 - 2016
N2 - Objective. To evaluate the cytoprotective effect of intravenous immunoglobulins (IVIGs) against endothelial cells. Subjects and methods. The cytotoxic effects of the sera obtained from 45 pregnant women against the endothelial cells treated with IVIGs were investigated using culture, an enzyme immunoassay, and flow cytometry. Results. After treatment of endothelial cells with IVIGs, there was a reduction in the cytotoxic effect of the sera obtained from the women with recurrent miscarriage against endothelial cells. Conclusion. IVIGs are effective cytoprotectors that are able to prevent abnormalities associated with endothelial damage and dysfunction.
AB - Objective. To evaluate the cytoprotective effect of intravenous immunoglobulins (IVIGs) against endothelial cells. Subjects and methods. The cytotoxic effects of the sera obtained from 45 pregnant women against the endothelial cells treated with IVIGs were investigated using culture, an enzyme immunoassay, and flow cytometry. Results. After treatment of endothelial cells with IVIGs, there was a reduction in the cytotoxic effect of the sera obtained from the women with recurrent miscarriage against endothelial cells. Conclusion. IVIGs are effective cytoprotectors that are able to prevent abnormalities associated with endothelial damage and dysfunction.
KW - ИММУНОГЛОБУЛИНЫ ДЛЯ ВНУТРИВЕННОГО ВВЕДЕНИЯ
KW - ЭНДОТЕЛИАЛЬНЫЕ КЛЕТКИ
KW - АНТИФОСФОЛИПИДНЫЙ СИНДРОМ
KW - НЕВЫНАШИВАНИЕ БЕРЕМЕННОСТИ
UR - http://www.scopus.com/inward/record.url?scp=84995436769&partnerID=8YFLogxK
U2 - 10.18565/aig.2016.5.82-88
DO - 10.18565/aig.2016.5.82-88
M3 - статья
AN - SCOPUS:84995436769
SP - 82
EP - 88
JO - Akusherstvo i Ginekologiya (Bulgaria)
JF - Akusherstvo i Ginekologiya (Bulgaria)
SN - 0300-9092
IS - 5
ER -
ID: 13375359