Research output: Contribution to journal › Article › peer-review
Современные представления о возможном участии алюминия в этиологии болезни Альцгеймера. / Чучина, Виктория Александровна; Иваненко, Наталья Борисовна; Губаль, Анна Романовна; Ганеев, А.А.; Зубакина, Е.А.; Безручко, М.М.; Литвинцев, Б.С.
In: ТОКСИКОЛОГИЧЕСКИЙ ВЕСТНИК, Vol. 3, No. 3, 18.07.2021, p. 10-15.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Современные представления о возможном участии алюминия в этиологии болезни Альцгеймера
AU - Чучина, Виктория Александровна
AU - Иваненко, Наталья Борисовна
AU - Губаль, Анна Романовна
AU - Ганеев, А.А.
AU - Зубакина, Е.А.
AU - Безручко, М.М.
AU - Литвинцев, Б.С.
PY - 2021/7/18
Y1 - 2021/7/18
N2 - The aim of the study was to investigate the possibility of using а concentration of aluminum as a marker of neurodegenerative diseases. Material and methods . To achieve this goal, there was carried out an analysis of literary origins from various databases, in particular Scopus and PubMed. Results . The analysis shows that by now there has been accumulated strong evidence that certain neurodegenerative diseases are associated with chronic exposure to low-dose of aluminum: in particular, Alzheimer's disease (AD); motor neuron disease or amyotrophic lateral sclerosis (ALS); multiple sclerosis (MS) and a number of others. Conclusion . Thus, it can be assumed that the measurement of the concentration of Al in the blood plasma will make it possible to identify a group people with of high risk of AD, which will allow starting preventive treatment at the earliest stage of the disease. The capabilities of the existing methods of analysis: atomic absorption spectrometry with electrothermal atomization (GFAAS) and inductively coupled plasma mass spectrometry (ICP-MS) enable to solve this problem.
AB - The aim of the study was to investigate the possibility of using а concentration of aluminum as a marker of neurodegenerative diseases. Material and methods . To achieve this goal, there was carried out an analysis of literary origins from various databases, in particular Scopus and PubMed. Results . The analysis shows that by now there has been accumulated strong evidence that certain neurodegenerative diseases are associated with chronic exposure to low-dose of aluminum: in particular, Alzheimer's disease (AD); motor neuron disease or amyotrophic lateral sclerosis (ALS); multiple sclerosis (MS) and a number of others. Conclusion . Thus, it can be assumed that the measurement of the concentration of Al in the blood plasma will make it possible to identify a group people with of high risk of AD, which will allow starting preventive treatment at the earliest stage of the disease. The capabilities of the existing methods of analysis: atomic absorption spectrometry with electrothermal atomization (GFAAS) and inductively coupled plasma mass spectrometry (ICP-MS) enable to solve this problem.
UR - https://www.mendeley.com/catalogue/2c078ed2-8cf5-332f-b80e-94bf94aa156d/
U2 - 10.36946/0869-7922-2021-29-3-10-15
DO - 10.36946/0869-7922-2021-29-3-10-15
M3 - статья
VL - 3
SP - 10
EP - 15
JO - ТОКСИКОЛОГИЧЕСКИЙ ВЕСТНИК
JF - ТОКСИКОЛОГИЧЕСКИЙ ВЕСТНИК
SN - 0869-7922
IS - 3
ER -
ID: 87797566