Standard

ВЛИЯНИЕ УНИФУЗОЛА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЭНДОТЕЛИЯ И МИКРОЦИРКУЛЯЦИЮ В ЭКСПЕРИМЕНТЕ. / Торопова, Я. Г.; ЗЕЛИНСКАЯ , И.А.; Печникова, Надежда Александровна; ГАЛАГУДЗА , М.М.; КОВАЛЕНКО, А.Л.

In: ЭКСПЕРИМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ, Vol. 81, No. 5, 2018, p. 7-11.

Research output: Contribution to journal › Article › peer-review

Harvard

Торопова, ЯГ, ЗЕЛИНСКАЯ , ИА, Печникова, НА, ГАЛАГУДЗА , ММ & КОВАЛЕНКО, АЛ 2018, 'ВЛИЯНИЕ УНИФУЗОЛА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЭНДОТЕЛИЯ И МИКРОЦИРКУЛЯЦИЮ В ЭКСПЕРИМЕНТЕ', ЭКСПЕРИМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ, vol. 81, no. 5, pp. 7-11. https://doi.org/10.30906/0869-2092-2018-81-5-7-11, https://doi.org/10.30906/0869-2092-2018-81-5-7-11

APA

Торопова, Я. Г., ЗЕЛИНСКАЯ , И. А., Печникова, Н. А., ГАЛАГУДЗА , М. М., & КОВАЛЕНКО, А. Л. (2018). ВЛИЯНИЕ УНИФУЗОЛА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЭНДОТЕЛИЯ И МИКРОЦИРКУЛЯЦИЮ В ЭКСПЕРИМЕНТЕ. ЭКСПЕРИМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ, 81(5), 7-11. https://doi.org/10.30906/0869-2092-2018-81-5-7-11, https://doi.org/10.30906/0869-2092-2018-81-5-7-11

Vancouver

Торопова ЯГ, ЗЕЛИНСКАЯ ИА, Печникова НА, ГАЛАГУДЗА ММ, КОВАЛЕНКО АЛ. ВЛИЯНИЕ УНИФУЗОЛА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЭНДОТЕЛИЯ И МИКРОЦИРКУЛЯЦИЮ В ЭКСПЕРИМЕНТЕ. ЭКСПЕРИМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ. 2018;81(5):7-11. https://doi.org/10.30906/0869-2092-2018-81-5-7-11, https://doi.org/10.30906/0869-2092-2018-81-5-7-11

Author

Торопова, Я. Г. ; ЗЕЛИНСКАЯ , И.А. ; Печникова, Надежда Александровна ; ГАЛАГУДЗА , М.М. ; КОВАЛЕНКО, А.Л. / ВЛИЯНИЕ УНИФУЗОЛА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЭНДОТЕЛИЯ И МИКРОЦИРКУЛЯЦИЮ В ЭКСПЕРИМЕНТЕ. In: ЭКСПЕРИМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ. 2018 ; Vol. 81, No. 5. pp. 7-11.

BibTeX

@article{8b0c62ed42e94153bf7b92f6a460f5df,
title = "ВЛИЯНИЕ УНИФУЗОЛА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЭНДОТЕЛИЯ И МИКРОЦИРКУЛЯЦИЮ В ЭКСПЕРИМЕНТЕ",
abstract = "Unifuzol (unifusol) has a pronounced endothelioprotective activity and is used as a supportive therapy of endothelium. The influence of unifuzol on the reactivity of mesenteric vessels in vitro and regional bloodstream was studied under conditions of model small intestine ischemia-reperfusion in rats. A dose dependence of these effects was observed. It was found that the drug injection to rats in all doses (52.5 - 210 mg/kg) ensured restoration of blood circulation in the small intestine to the base (pre-ischemic) level in the reperfusion period. Data of myography showed that unifuzol significantly increased both the contractile and relaxing ability of vessels. Significant endothelioprotective effect of unifuzol is a pathogenetic justification for its further study as a complex medicine for angioprotection in pathologies accompanied by endothelial dysfunction.",
keywords = "Endothelium, Microcirculation, Rats, Small intestine ischemia-reperfusion, Unifuzol, Wire myography",
author = "Торопова, {Я. Г.} and И.А. ЗЕЛИНСКАЯ and Печникова, {Надежда Александровна} and М.М. ГАЛАГУДЗА and А.Л. КОВАЛЕНКО",
note = "Publisher Copyright: {\textcopyright} 2018 Izdatel'stvo Meditsina. All rights reserved.",
year = "2018",
doi = "10.30906/0869-2092-2018-81-5-7-11",
language = "русский",
volume = "81",
pages = "7--11",
journal = "ЭКСПЕРИМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ",
issn = "0869-2092",
publisher = "Медицина",
number = "5",

}

RIS

TY - JOUR

T1 - ВЛИЯНИЕ УНИФУЗОЛА НА ФУНКЦИОНАЛЬНОЕ СОСТОЯНИЕ ЭНДОТЕЛИЯ И МИКРОЦИРКУЛЯЦИЮ В ЭКСПЕРИМЕНТЕ

AU - Торопова, Я. Г.

AU - ЗЕЛИНСКАЯ , И.А.

AU - Печникова, Надежда Александровна

AU - ГАЛАГУДЗА , М.М.

AU - КОВАЛЕНКО, А.Л.

N1 - Publisher Copyright: © 2018 Izdatel'stvo Meditsina. All rights reserved.

PY - 2018

Y1 - 2018

N2 - Unifuzol (unifusol) has a pronounced endothelioprotective activity and is used as a supportive therapy of endothelium. The influence of unifuzol on the reactivity of mesenteric vessels in vitro and regional bloodstream was studied under conditions of model small intestine ischemia-reperfusion in rats. A dose dependence of these effects was observed. It was found that the drug injection to rats in all doses (52.5 - 210 mg/kg) ensured restoration of blood circulation in the small intestine to the base (pre-ischemic) level in the reperfusion period. Data of myography showed that unifuzol significantly increased both the contractile and relaxing ability of vessels. Significant endothelioprotective effect of unifuzol is a pathogenetic justification for its further study as a complex medicine for angioprotection in pathologies accompanied by endothelial dysfunction.

AB - Unifuzol (unifusol) has a pronounced endothelioprotective activity and is used as a supportive therapy of endothelium. The influence of unifuzol on the reactivity of mesenteric vessels in vitro and regional bloodstream was studied under conditions of model small intestine ischemia-reperfusion in rats. A dose dependence of these effects was observed. It was found that the drug injection to rats in all doses (52.5 - 210 mg/kg) ensured restoration of blood circulation in the small intestine to the base (pre-ischemic) level in the reperfusion period. Data of myography showed that unifuzol significantly increased both the contractile and relaxing ability of vessels. Significant endothelioprotective effect of unifuzol is a pathogenetic justification for its further study as a complex medicine for angioprotection in pathologies accompanied by endothelial dysfunction.

KW - Endothelium

KW - Microcirculation

KW - Rats

KW - Small intestine ischemia-reperfusion

KW - Unifuzol

KW - Wire myography

UR - http://www.scopus.com/inward/record.url?scp=85052193969&partnerID=8YFLogxK

U2 - 10.30906/0869-2092-2018-81-5-7-11

DO - 10.30906/0869-2092-2018-81-5-7-11

M3 - статья

AN - SCOPUS:85052193969

VL - 81

SP - 7

EP - 11

JO - ЭКСПЕРИМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ

JF - ЭКСПЕРИМЕНТАЛЬНАЯ И КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ

SN - 0869-2092

IS - 5

ER -

ID: 85245206