Research output: Contribution to journal › Review article › peer-review
Таксономический дисбиоз кишечника при целиакии и перспективы его коррекции. / Балукова, Екатерина Владимировна; Хавкин, Анатолий Ильич; Новикова, Валерия Павловна; Беляева, Юлия Сергеевна; Налетов, Андрей Васильевич.
In: ПЕДИАТРИЧЕСКАЯ ФАРМАКОЛОГИЯ, Vol. 23, No. 3, 27.07.2026, p. 297–302.Research output: Contribution to journal › Review article › peer-review
}
TY - JOUR
T1 - Таксономический дисбиоз кишечника при целиакии и перспективы его коррекции
AU - Балукова, Екатерина Владимировна
AU - Хавкин, Анатолий Ильич
AU - Новикова, Валерия Павловна
AU - Беляева, Юлия Сергеевна
AU - Налетов, Андрей Васильевич
PY - 2026/7/27
Y1 - 2026/7/27
N2 - Not only genetic predisposition, but also environmental factors lead to celiac disease development in a patient. The question of whether intestinal dysbiosis is disease cause or consequence remains opened. This review presents current achievements in studying correlations between intestinal microbiota state and celiac disease development, as well as evaluates methods for microbial imbalance correction in affecting disease pathogenetic mechanisms. Based on current studies analysis, it can be concluded that any microbiota changes in patients with celiac disease should be considered not only because of the disease, but also as part of complex of interacting causal factors, including dietary and psychosocial aspects. Potential probiotics strengths are associated with restoration of intestinal microflora composition and immune response modulation. Altogether, it increases resistance to pathogens and may reduce gastrointestinal symptoms severity in patients on gluten-free diet.
AB - Not only genetic predisposition, but also environmental factors lead to celiac disease development in a patient. The question of whether intestinal dysbiosis is disease cause or consequence remains opened. This review presents current achievements in studying correlations between intestinal microbiota state and celiac disease development, as well as evaluates methods for microbial imbalance correction in affecting disease pathogenetic mechanisms. Based on current studies analysis, it can be concluded that any microbiota changes in patients with celiac disease should be considered not only because of the disease, but also as part of complex of interacting causal factors, including dietary and psychosocial aspects. Potential probiotics strengths are associated with restoration of intestinal microflora composition and immune response modulation. Altogether, it increases resistance to pathogens and may reduce gastrointestinal symptoms severity in patients on gluten-free diet.
KW - celiac disease
KW - gluten-free diet
KW - intestinal microbiota
KW - probiotic therapy
UR - https://www.mendeley.com/catalogue/12e4cfa2-e223-32ad-9b29-5d37ce4abcc1/
U2 - 10.15690/pf.v23i3.3039
DO - 10.15690/pf.v23i3.3039
M3 - Обзорная статья
VL - 23
SP - 297
EP - 302
JO - Pediatricheskaya Farmakologiya
JF - Pediatricheskaya Farmakologiya
SN - 1727-5776
IS - 3
ER -
ID: 143430447