The victory of Joseph Biden in the 2020 presidential election sparked discourse about the upcoming changes in U.S. foreign policy. The return of an experienced politician and specialist in international relations to the White House was inevitably associated with a breakthrough in American public diplomacy, which had stagnated under President Donald Trump in 2017–2021. Digital propaganda, analytics of Big Data and integration of new technologies into information policy have become the leading areas of modern foreign policy influence and require careful attention from the American leadership. Political scientists who are closest to the real process of making foreign policy decisions have prepared a number of analytical reports with recommendations for the new president. Such development paths can be conditionally divided into three scenarios: active, passive and intermediate. The active scenario presupposes a “radical revolution” of the institutions of governance, vectors and paradigms of American public diplomacy. The passive scenario implies further stagnation of American strategic communications without fundamental changes. Finally, an intermediate or moderate scenario is aimed at the collaboration of active and passive tracks in the development of public diplomacy, in which the paradigms of U.S. public diplomacy can be radically changed, and the institutional level of their implementation, at the same time, will remain without significant reformation. Based on a set of official documents, public statements by members of the new presidential administration and articles of the American expert community, the author assesses the new directions of American strategic communications and data diplomacy, and also emphasizes the need for further study of modern public diplomacy, taking into account new trends in its implementation. The conclusions of the article will be useful to all researchers of U.S. foreign policy and the digitalization of international relations.