Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
Zebrafish models for studying cognitive enhancers. / Kolesnikova, Tatiana O.; Demin, Konstantin A.; Costa, Fabiano V.; de Abreu, Murilo S.; Kalueff, Allan V.
в: Neuroscience and Biobehavioral Reviews, Том 164, 105797, 09.2024.Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование
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TY - JOUR
T1 - Zebrafish models for studying cognitive enhancers
AU - Kolesnikova, Tatiana O.
AU - Demin, Konstantin A.
AU - Costa, Fabiano V.
AU - de Abreu, Murilo S.
AU - Kalueff, Allan V.
N1 - Tatiana O. Kolesnikova, Konstantin A. Demin, Fabiano V. Costa, Murilo S. de Abreu, Allan V. Kalueff. Zebrafish models for studying cognitive enhancers. In Press, Journal Pre-proof. 4 July 2024, 105797. doi. 10.1016/j.neubiorev.2024.105797
PY - 2024/9
Y1 - 2024/9
N2 - Cognitive decline is commonly seen both in normal aging and in neurodegenerative and neuropsychiatric diseases. Various experimental animal models represent a valuable tool to study brain cognitive processes and their deficits. Equally important is the search for novel drugs to treat cognitive deficits and improve cognitions. Complementing rodent and clinical findings, studies utilizing zebrafish (Danio rerio) are rapidly gaining popularity in translational cognitive research and neuroactive drug screening. Here, we discuss the value of zebrafish models and assays for screening nootropic (cognitive enhancer) drugs and the discovery of novel nootropics. We also discuss the existing challenges, and outline future directions of research in this field.
AB - Cognitive decline is commonly seen both in normal aging and in neurodegenerative and neuropsychiatric diseases. Various experimental animal models represent a valuable tool to study brain cognitive processes and their deficits. Equally important is the search for novel drugs to treat cognitive deficits and improve cognitions. Complementing rodent and clinical findings, studies utilizing zebrafish (Danio rerio) are rapidly gaining popularity in translational cognitive research and neuroactive drug screening. Here, we discuss the value of zebrafish models and assays for screening nootropic (cognitive enhancer) drugs and the discovery of novel nootropics. We also discuss the existing challenges, and outline future directions of research in this field.
KW - Cognition
KW - Cognitive enhancers
KW - Neurodegenerative disorders
KW - Nootropics
KW - Zebrafish
UR - https://www.mendeley.com/catalogue/4e93305e-f600-3ab7-ab66-84b313034123/
U2 - 10.1016/j.neubiorev.2024.105797
DO - 10.1016/j.neubiorev.2024.105797
M3 - Review article
C2 - 38971515
VL - 164
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
SN - 0149-7634
M1 - 105797
ER -
ID: 121669201