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Zebrafish as an emerging model for studying complex brain disorders. / Kalueff, Allan V.; Stewart, Adam Michael; Gerlai, Robert.

в: Trends in Pharmacological Sciences, Том 35, № 2, 02.2014, стр. 63-75.

Результаты исследований: Научные публикации в периодических изданиях › Обзорная статья › Рецензирование

Harvard

Kalueff, AV, Stewart, AM & Gerlai, R 2014, 'Zebrafish as an emerging model for studying complex brain disorders', Trends in Pharmacological Sciences, Том. 35, № 2, стр. 63-75. https://doi.org/10.1016/j.tips.2013.12.002

APA

Kalueff, A. V., Stewart, A. M., & Gerlai, R. (2014). Zebrafish as an emerging model for studying complex brain disorders. Trends in Pharmacological Sciences, 35(2), 63-75. https://doi.org/10.1016/j.tips.2013.12.002

Vancouver

Kalueff AV, Stewart AM, Gerlai R. Zebrafish as an emerging model for studying complex brain disorders. Trends in Pharmacological Sciences. 2014 Февр.;35(2):63-75. https://doi.org/10.1016/j.tips.2013.12.002

Author

Kalueff, Allan V. ; Stewart, Adam Michael ; Gerlai, Robert. / Zebrafish as an emerging model for studying complex brain disorders. в: Trends in Pharmacological Sciences. 2014 ; Том 35, № 2. стр. 63-75.

BibTeX

@article{592b143413854a3097826eac55e95601,
title = "Zebrafish as an emerging model for studying complex brain disorders",
abstract = "The zebrafish (Danio rerio) is rapidly becoming a popular model organism in pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently used to increase our understanding of brain function, dysfunction, and their genetic and pharmacological modulation. Here we review the developing utility of zebrafish in the analysis of complex brain disorders (including, e.g., depression, autism, psychoses, drug abuse, and cognitive deficits), also covering zebrafish applications towards the goal of modeling major human neuropsychiatric and drug-induced syndromes. We argue that zebrafish models of complex brain disorders and drug-induced conditions are a rapidly emerging critical field in translational neuroscience and pharmacology research.",
keywords = "behavioral tests, brain disorders, translational research, zebrafish",
author = "Kalueff, {Allan V.} and Stewart, {Adam Michael} and Robert Gerlai",
note = "Funding Information: The authors acknowledge help of many members of the Kalueff Laboratory at Tulane University and the ZENEREI Institute for developing illustrations for this manuscript. We thank Dr. L. Noldus (Noldus IT, Netherlands), Dr. R. Mervis (University of South Florida, USA) and their research teams for providing illustrations for panels in Figure 1 , based on our collaborative projects. The authors{\textquoteright} research has been supported by grants from the National Institutes of Health (NIAAA AA015325-01A2 to R.G., and NIDA DA030900-02 to A.V.K.).",
year = "2014",
month = feb,
doi = "10.1016/j.tips.2013.12.002",
language = "English",
volume = "35",
pages = "63--75",
journal = "Trends in Pharmacological Sciences",
issn = "0165-6147",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Zebrafish as an emerging model for studying complex brain disorders

AU - Kalueff, Allan V.

AU - Stewart, Adam Michael

AU - Gerlai, Robert

N1 - Funding Information: The authors acknowledge help of many members of the Kalueff Laboratory at Tulane University and the ZENEREI Institute for developing illustrations for this manuscript. We thank Dr. L. Noldus (Noldus IT, Netherlands), Dr. R. Mervis (University of South Florida, USA) and their research teams for providing illustrations for panels in Figure 1 , based on our collaborative projects. The authors’ research has been supported by grants from the National Institutes of Health (NIAAA AA015325-01A2 to R.G., and NIDA DA030900-02 to A.V.K.).

PY - 2014/2

Y1 - 2014/2

N2 - The zebrafish (Danio rerio) is rapidly becoming a popular model organism in pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently used to increase our understanding of brain function, dysfunction, and their genetic and pharmacological modulation. Here we review the developing utility of zebrafish in the analysis of complex brain disorders (including, e.g., depression, autism, psychoses, drug abuse, and cognitive deficits), also covering zebrafish applications towards the goal of modeling major human neuropsychiatric and drug-induced syndromes. We argue that zebrafish models of complex brain disorders and drug-induced conditions are a rapidly emerging critical field in translational neuroscience and pharmacology research.

AB - The zebrafish (Danio rerio) is rapidly becoming a popular model organism in pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently used to increase our understanding of brain function, dysfunction, and their genetic and pharmacological modulation. Here we review the developing utility of zebrafish in the analysis of complex brain disorders (including, e.g., depression, autism, psychoses, drug abuse, and cognitive deficits), also covering zebrafish applications towards the goal of modeling major human neuropsychiatric and drug-induced syndromes. We argue that zebrafish models of complex brain disorders and drug-induced conditions are a rapidly emerging critical field in translational neuroscience and pharmacology research.

KW - behavioral tests

KW - brain disorders

KW - translational research

KW - zebrafish

UR - http://www.scopus.com/inward/record.url?scp=84895076713&partnerID=8YFLogxK

U2 - 10.1016/j.tips.2013.12.002

DO - 10.1016/j.tips.2013.12.002

M3 - Review article

C2 - 24412421

AN - SCOPUS:84895076713

VL - 35

SP - 63

EP - 75

JO - Trends in Pharmacological Sciences

JF - Trends in Pharmacological Sciences

SN - 0165-6147

IS - 2

ER -

ID: 100859042