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Zebrafish as a Model of Neurodevelopmental Disorders. / de Abreu, Murilo S; Genario, Rafael; Giacomini, Ana C V V; Demin, Konstantin A; Lakstygal, Anton M; Amstislavskaya, Tamara G; Fontana, Barbara Dotto; Parker, Matthew O; Kalueff, Allan V.

в: Neuroscience, 08.2019.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

de Abreu, MS, Genario, R, Giacomini, ACVV, Demin, KA, Lakstygal, AM, Amstislavskaya, TG, Fontana, BD, Parker, MO & Kalueff, AV 2019, 'Zebrafish as a Model of Neurodevelopmental Disorders', Neuroscience. https://doi.org/10.1016/j.neuroscience.2019.08.034

APA

de Abreu, M. S., Genario, R., Giacomini, A. C. V. V., Demin, K. A., Lakstygal, A. M., Amstislavskaya, T. G., Fontana, B. D., Parker, M. O., & Kalueff, A. V. (2019). Zebrafish as a Model of Neurodevelopmental Disorders. Neuroscience. https://doi.org/10.1016/j.neuroscience.2019.08.034

Vancouver

de Abreu MS, Genario R, Giacomini ACVV, Demin KA, Lakstygal AM, Amstislavskaya TG и пр. Zebrafish as a Model of Neurodevelopmental Disorders. Neuroscience. 2019 Авг. https://doi.org/10.1016/j.neuroscience.2019.08.034

Author

de Abreu, Murilo S ; Genario, Rafael ; Giacomini, Ana C V V ; Demin, Konstantin A ; Lakstygal, Anton M ; Amstislavskaya, Tamara G ; Fontana, Barbara Dotto ; Parker, Matthew O ; Kalueff, Allan V. / Zebrafish as a Model of Neurodevelopmental Disorders. в: Neuroscience. 2019.

BibTeX

@article{d7a80241cbec44fba39a7471286e3be3,
title = "Zebrafish as a Model of Neurodevelopmental Disorders",
abstract = "Neurodevelopmental disorders (NDDs) caused by aberrant brain growth and development are life-long, debilitating illnesses that markedly impair the quality of life. Animal models are a valuable tool for studying NDD pathobiology and therapies. Mounting evidence suggests the zebrafish (Danio rerio) as a useful model organism to study NDDs, possessing both high physiological homology to humans and sensitivity to pharmacological and genetic manipulations. Here, we summarize experimental models of NDDs in zebrafish and highlight the growing translational significance of zebrafish NDD-related phenotypes. We also emphasize the need in further development of zebrafish models of NDDs to improve our understanding of their pathogenesis and therapeutic treatments.",
keywords = "animal models, attention-deficit/hyperactivity disorder, autism, genetic models, neurodevelopment",
author = "{de Abreu}, {Murilo S} and Rafael Genario and Giacomini, {Ana C V V} and Demin, {Konstantin A} and Lakstygal, {Anton M} and Amstislavskaya, {Tamara G} and Fontana, {Barbara Dotto} and Parker, {Matthew O} and Kalueff, {Allan V}",
note = "Copyright {\textcopyright} 2019 IBRO. Published by Elsevier Ltd. All rights reserved.",
year = "2019",
month = aug,
doi = "10.1016/j.neuroscience.2019.08.034",
language = "English",
journal = "Neuroscience",
issn = "0306-4522",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Zebrafish as a Model of Neurodevelopmental Disorders

AU - de Abreu, Murilo S

AU - Genario, Rafael

AU - Giacomini, Ana C V V

AU - Demin, Konstantin A

AU - Lakstygal, Anton M

AU - Amstislavskaya, Tamara G

AU - Fontana, Barbara Dotto

AU - Parker, Matthew O

AU - Kalueff, Allan V

N1 - Copyright © 2019 IBRO. Published by Elsevier Ltd. All rights reserved.

PY - 2019/8

Y1 - 2019/8

N2 - Neurodevelopmental disorders (NDDs) caused by aberrant brain growth and development are life-long, debilitating illnesses that markedly impair the quality of life. Animal models are a valuable tool for studying NDD pathobiology and therapies. Mounting evidence suggests the zebrafish (Danio rerio) as a useful model organism to study NDDs, possessing both high physiological homology to humans and sensitivity to pharmacological and genetic manipulations. Here, we summarize experimental models of NDDs in zebrafish and highlight the growing translational significance of zebrafish NDD-related phenotypes. We also emphasize the need in further development of zebrafish models of NDDs to improve our understanding of their pathogenesis and therapeutic treatments.

AB - Neurodevelopmental disorders (NDDs) caused by aberrant brain growth and development are life-long, debilitating illnesses that markedly impair the quality of life. Animal models are a valuable tool for studying NDD pathobiology and therapies. Mounting evidence suggests the zebrafish (Danio rerio) as a useful model organism to study NDDs, possessing both high physiological homology to humans and sensitivity to pharmacological and genetic manipulations. Here, we summarize experimental models of NDDs in zebrafish and highlight the growing translational significance of zebrafish NDD-related phenotypes. We also emphasize the need in further development of zebrafish models of NDDs to improve our understanding of their pathogenesis and therapeutic treatments.

KW - animal models

KW - attention-deficit/hyperactivity disorder

KW - autism

KW - genetic models

KW - neurodevelopment

UR - http://www.scopus.com/inward/record.url?scp=85075860800&partnerID=8YFLogxK

UR - http://www.mendeley.com/research/zebrafish-model-neurodevelopmental-disorders

U2 - 10.1016/j.neuroscience.2019.08.034

DO - 10.1016/j.neuroscience.2019.08.034

M3 - Article

C2 - 31472215

JO - Neuroscience

JF - Neuroscience

SN - 0306-4522

ER -

ID: 46340655