A comparative analysis of Bos taurus L. cytogenetic maps of different resolution levels was used to study principles of fusion R(G)-bands during chromosome condensation from prophase to the late metaphase. Three different types of fusion have been demonstrated, differing in quantity of interacting bands and fusion mechanism. Preferential condensation zones with constant localization was found. By means of the fusion index, faster condensation of R-bands than that of G-bands was revealed. Relevant data on B. taurus and Homo sapiens were compared. The obtained results are discussed in terms of common problems of mitotic chromosome R(G)-banding nature in warm-blooded animals.