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Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. / Sinenko, Sergey A.; Kim, Eun Kyung; Wynn, Rhoda; Manfruelli, Pascal; Ando, Istvan; Wharton, Kristi A.; Perrimon, Norbert; Mathey-Prevot, Bernard.

в: Developmental Biology, Том 273, № 1, 01.09.2004, стр. 48-62.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Sinenko, SA, Kim, EK, Wynn, R, Manfruelli, P, Ando, I, Wharton, KA, Perrimon, N & Mathey-Prevot, B 2004, 'Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development', Developmental Biology, Том. 273, № 1, стр. 48-62. https://doi.org/10.1016/j.ydbio.2004.05.022

APA

Sinenko, S. A., Kim, E. K., Wynn, R., Manfruelli, P., Ando, I., Wharton, K. A., Perrimon, N., & Mathey-Prevot, B. (2004). Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. Developmental Biology, 273(1), 48-62. https://doi.org/10.1016/j.ydbio.2004.05.022

Vancouver

Sinenko SA, Kim EK, Wynn R, Manfruelli P, Ando I, Wharton KA и пр. Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. Developmental Biology. 2004 Сент. 1;273(1):48-62. https://doi.org/10.1016/j.ydbio.2004.05.022

Author

Sinenko, Sergey A. ; Kim, Eun Kyung ; Wynn, Rhoda ; Manfruelli, Pascal ; Ando, Istvan ; Wharton, Kristi A. ; Perrimon, Norbert ; Mathey-Prevot, Bernard. / Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. в: Developmental Biology. 2004 ; Том 273, № 1. стр. 48-62.

BibTeX

@article{9805bfd79f2349de801827a0281832e3,
title = "Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development",
abstract = "To identify novel factors involved in Drosophila hematopoiesis, we screened a collection of lethal recessive mutations that also affected normal hemocyte composition in larvae. We present the characterization of the gene yantar (ytr) for which we isolated null and hypomorphic mutations that were associated with severe defects in hemocyte differentiation and proliferation; ytr is predominantly expressed in the hematopoietic tissue during larval development and encodes an evolutionary conserved protein which is predominantly localized in the nucleus. The hematopoietic phenotype in ytr mutants is consistent with a defect or block in differentiation of precursor hemocytes: mutant larvae have enlarged lymph glands (LGs) and have an excess of circulating hemocytes. In addition, many cells exhibit both lamellocyte and crystal cell markers. Ytr function has been preserved in evolution as hematopoietic specific expression of the Drosophila or mouse Ytr proteins rescue the differentiation defects in mutant hemocytes.",
keywords = "Hemocyte development, Lamellocytes, Lozenge, Lymph glands, Melanotic masses, Yantar",
author = "Sinenko, {Sergey A.} and Kim, {Eun Kyung} and Rhoda Wynn and Pascal Manfruelli and Istvan Ando and Wharton, {Kristi A.} and Norbert Perrimon and Bernard Mathey-Prevot",
year = "2004",
month = sep,
day = "1",
doi = "10.1016/j.ydbio.2004.05.022",
language = "English",
volume = "273",
pages = "48--62",
journal = "Developmental Biology",
issn = "0012-1606",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development

AU - Sinenko, Sergey A.

AU - Kim, Eun Kyung

AU - Wynn, Rhoda

AU - Manfruelli, Pascal

AU - Ando, Istvan

AU - Wharton, Kristi A.

AU - Perrimon, Norbert

AU - Mathey-Prevot, Bernard

PY - 2004/9/1

Y1 - 2004/9/1

N2 - To identify novel factors involved in Drosophila hematopoiesis, we screened a collection of lethal recessive mutations that also affected normal hemocyte composition in larvae. We present the characterization of the gene yantar (ytr) for which we isolated null and hypomorphic mutations that were associated with severe defects in hemocyte differentiation and proliferation; ytr is predominantly expressed in the hematopoietic tissue during larval development and encodes an evolutionary conserved protein which is predominantly localized in the nucleus. The hematopoietic phenotype in ytr mutants is consistent with a defect or block in differentiation of precursor hemocytes: mutant larvae have enlarged lymph glands (LGs) and have an excess of circulating hemocytes. In addition, many cells exhibit both lamellocyte and crystal cell markers. Ytr function has been preserved in evolution as hematopoietic specific expression of the Drosophila or mouse Ytr proteins rescue the differentiation defects in mutant hemocytes.

AB - To identify novel factors involved in Drosophila hematopoiesis, we screened a collection of lethal recessive mutations that also affected normal hemocyte composition in larvae. We present the characterization of the gene yantar (ytr) for which we isolated null and hypomorphic mutations that were associated with severe defects in hemocyte differentiation and proliferation; ytr is predominantly expressed in the hematopoietic tissue during larval development and encodes an evolutionary conserved protein which is predominantly localized in the nucleus. The hematopoietic phenotype in ytr mutants is consistent with a defect or block in differentiation of precursor hemocytes: mutant larvae have enlarged lymph glands (LGs) and have an excess of circulating hemocytes. In addition, many cells exhibit both lamellocyte and crystal cell markers. Ytr function has been preserved in evolution as hematopoietic specific expression of the Drosophila or mouse Ytr proteins rescue the differentiation defects in mutant hemocytes.

KW - Hemocyte development

KW - Lamellocytes

KW - Lozenge

KW - Lymph glands

KW - Melanotic masses

KW - Yantar

UR - http://www.scopus.com/inward/record.url?scp=4043082749&partnerID=8YFLogxK

U2 - 10.1016/j.ydbio.2004.05.022

DO - 10.1016/j.ydbio.2004.05.022

M3 - Article

AN - SCOPUS:4043082749

VL - 273

SP - 48

EP - 62

JO - Developmental Biology

JF - Developmental Biology

SN - 0012-1606

IS - 1

ER -

ID: 50502386