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Whole genome sequencing data and analyses of the underlying SUP35 transcriptional regulation for a Saccharomyces cerevisiae nonsense suppressor mutant. / Matveenko, Andrew G.; Drozdova, Polina B.; Moskalenko, Svetlana E.; Tarasov, Oleg V.; Zhouravleva, Galina A.

в: Data in Brief, Том 23, 103694, 01.04.2019.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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@article{bc91788e858746dda08a1ae1756c1f93,
title = "Whole genome sequencing data and analyses of the underlying SUP35 transcriptional regulation for a Saccharomyces cerevisiae nonsense suppressor mutant",
abstract = "Termination of translation in eukaryotes is governed by two release factors encoded by the SUP45 and SUP35 genes in Saccharomyces cerevisiae. Previously, a set of mutations in these genes had been obtained. However, the exact sequence change associated with one mutation, sup35-222, was not identified by Sanger sequencing of the SUP35 region. Presented here are whole-genome sequencing data for the sup35-222 strain, data on copy number variation in its genome along with supporting pulse-field gel electrophoresis experiment data, and the list of single-nucleotide variations that differentiate this strain and its wild-type ancestor. One substitution upstream the SUP35 gene was located in a sequence corresponding to the Abf1-binding site. Data obtained from the introduction of this variation from sup35-222 strain into a different wild-type strain, specifically, detection of a nonsense-suppressor phenotype accompanied by a decrease in the Sup35 protein level, are also presented in this article.",
keywords = "YEAST, MUTATIONS, STABILITY, FORMAT, SUP45",
author = "Matveenko, {Andrew G.} and Drozdova, {Polina B.} and Moskalenko, {Svetlana E.} and Tarasov, {Oleg V.} and Zhouravleva, {Galina A.}",
year = "2019",
month = apr,
day = "1",
doi = "10.1016/j.dib.2019.01.042",
language = "English",
volume = "23",
journal = "Data in Brief",
issn = "2352-3409",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Whole genome sequencing data and analyses of the underlying SUP35 transcriptional regulation for a Saccharomyces cerevisiae nonsense suppressor mutant

AU - Matveenko, Andrew G.

AU - Drozdova, Polina B.

AU - Moskalenko, Svetlana E.

AU - Tarasov, Oleg V.

AU - Zhouravleva, Galina A.

PY - 2019/4/1

Y1 - 2019/4/1

N2 - Termination of translation in eukaryotes is governed by two release factors encoded by the SUP45 and SUP35 genes in Saccharomyces cerevisiae. Previously, a set of mutations in these genes had been obtained. However, the exact sequence change associated with one mutation, sup35-222, was not identified by Sanger sequencing of the SUP35 region. Presented here are whole-genome sequencing data for the sup35-222 strain, data on copy number variation in its genome along with supporting pulse-field gel electrophoresis experiment data, and the list of single-nucleotide variations that differentiate this strain and its wild-type ancestor. One substitution upstream the SUP35 gene was located in a sequence corresponding to the Abf1-binding site. Data obtained from the introduction of this variation from sup35-222 strain into a different wild-type strain, specifically, detection of a nonsense-suppressor phenotype accompanied by a decrease in the Sup35 protein level, are also presented in this article.

AB - Termination of translation in eukaryotes is governed by two release factors encoded by the SUP45 and SUP35 genes in Saccharomyces cerevisiae. Previously, a set of mutations in these genes had been obtained. However, the exact sequence change associated with one mutation, sup35-222, was not identified by Sanger sequencing of the SUP35 region. Presented here are whole-genome sequencing data for the sup35-222 strain, data on copy number variation in its genome along with supporting pulse-field gel electrophoresis experiment data, and the list of single-nucleotide variations that differentiate this strain and its wild-type ancestor. One substitution upstream the SUP35 gene was located in a sequence corresponding to the Abf1-binding site. Data obtained from the introduction of this variation from sup35-222 strain into a different wild-type strain, specifically, detection of a nonsense-suppressor phenotype accompanied by a decrease in the Sup35 protein level, are also presented in this article.

KW - YEAST

KW - MUTATIONS

KW - STABILITY

KW - FORMAT

KW - SUP45

UR - http://www.scopus.com/inward/record.url?scp=85061189850&partnerID=8YFLogxK

U2 - 10.1016/j.dib.2019.01.042

DO - 10.1016/j.dib.2019.01.042

M3 - Article

AN - SCOPUS:85061189850

VL - 23

JO - Data in Brief

JF - Data in Brief

SN - 2352-3409

M1 - 103694

ER -

ID: 47423356