Transepithelial potential difference in the goat mammary gland and its change during hand milking, and administration of oxytocin and catecholamines

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Transepithelial potential difference in the goat mammary gland and its change during hand milking, and administration of oxytocin and catecholamines. / Alekseev, Nikolaj P.; Markov, Alexander G.; Tolkunov, Yuri A.

в: Journal of Dairy Research, Том 59, № 4, 11.1992, стр. 469-478.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{46073ea2f0b04f0899b5acfc4b647a33,

title = "Transepithelial potential difference in the goat mammary gland and its change during hand milking, and administration of oxytocin and catecholamines",

abstract = "The reaction of secretory epithelium and myoepithelial cells in the alveoli to hand milking and i.v. injection of oxytocin and catecholamines was studied in lactating goats. The reaction of secretory cells was assessed by changes in the transepithelial (blood-milk) potential difference (PD), and the contractile reaction of myoepithelial cells by the growth of intramammary pressure (IP). The initial value of PD was 24.6 ±0.6 mV, that of IP 3.32 ± 0.08 kPa (24.9 ± 0.6 mmHg). Milking and oxytocin administration caused a rise in PD and an increase in IP. After noradrenaline and adrenaline injections two-phase PD changes and a short–term rise in IP were recorded. Isoproterenol, a β-agonist, caused a rise in PD but did not affect IP. Phenylephrine, an α-agonist, caused two-phase and one-phase changes in PD. Simultaneously, a rise in IP was recorded. The results show that the reaction of the mammary gland to the substances administered is complex. Myoepithelial and secretory cells respond differently to short-term rises in the level of mediators and hormones in the blood.",

author = "Alekseev, {Nikolaj P.} and Markov, {Alexander G.} and Tolkunov, {Yuri A.}",

year = "1992",

month = nov,

doi = "10.1017/S0022029900027138",

language = "English",

volume = "59",

pages = "469--478",

journal = "Journal of Dairy Research",

issn = "0022-0299",

publisher = "Cambridge University Press",

number = "4",

}

RIS

TY - JOUR

T1 - Transepithelial potential difference in the goat mammary gland and its change during hand milking, and administration of oxytocin and catecholamines

AU - Alekseev, Nikolaj P.

AU - Markov, Alexander G.

AU - Tolkunov, Yuri A.

PY - 1992/11

Y1 - 1992/11

N2 - The reaction of secretory epithelium and myoepithelial cells in the alveoli to hand milking and i.v. injection of oxytocin and catecholamines was studied in lactating goats. The reaction of secretory cells was assessed by changes in the transepithelial (blood-milk) potential difference (PD), and the contractile reaction of myoepithelial cells by the growth of intramammary pressure (IP). The initial value of PD was 24.6 ±0.6 mV, that of IP 3.32 ± 0.08 kPa (24.9 ± 0.6 mmHg). Milking and oxytocin administration caused a rise in PD and an increase in IP. After noradrenaline and adrenaline injections two-phase PD changes and a short–term rise in IP were recorded. Isoproterenol, a β-agonist, caused a rise in PD but did not affect IP. Phenylephrine, an α-agonist, caused two-phase and one-phase changes in PD. Simultaneously, a rise in IP was recorded. The results show that the reaction of the mammary gland to the substances administered is complex. Myoepithelial and secretory cells respond differently to short-term rises in the level of mediators and hormones in the blood.

AB - The reaction of secretory epithelium and myoepithelial cells in the alveoli to hand milking and i.v. injection of oxytocin and catecholamines was studied in lactating goats. The reaction of secretory cells was assessed by changes in the transepithelial (blood-milk) potential difference (PD), and the contractile reaction of myoepithelial cells by the growth of intramammary pressure (IP). The initial value of PD was 24.6 ±0.6 mV, that of IP 3.32 ± 0.08 kPa (24.9 ± 0.6 mmHg). Milking and oxytocin administration caused a rise in PD and an increase in IP. After noradrenaline and adrenaline injections two-phase PD changes and a short–term rise in IP were recorded. Isoproterenol, a β-agonist, caused a rise in PD but did not affect IP. Phenylephrine, an α-agonist, caused two-phase and one-phase changes in PD. Simultaneously, a rise in IP was recorded. The results show that the reaction of the mammary gland to the substances administered is complex. Myoepithelial and secretory cells respond differently to short-term rises in the level of mediators and hormones in the blood.

UR - http://www.scopus.com/inward/record.url?scp=0026950122&partnerID=8YFLogxK

U2 - 10.1017/S0022029900027138

DO - 10.1017/S0022029900027138

M3 - Article

C2 - 1452832

AN - SCOPUS:0026950122

VL - 59

SP - 469

EP - 478

JO - Journal of Dairy Research

JF - Journal of Dairy Research

SN - 0022-0299

IS - 4

ER -

ID: 69896853