In present work an enthalpies of solution at infinite dilution and solvation of ethers (diethyl ether, diglyme, 1,4-dioxane, 12-crown-4 and 15-crown-5) in aliphatic alcohols at 298.15 K and enthalpies of aliphatic alcohols, alkanes in ethers were determined. The enthalpies of hydrogen bonding for these systems were calculated using experimental data. The hydrogen bond enthalpies of ethers in alcohols are significantly lower by absolute values than the enthalpies of hydrogen bonding in the complexes 1:1 of alcohols in ethers solution due to reorganization effects of aliphatic alcohols as a solvent (breaking of solvent-solvent hydrogen bonds). The cooperative effects in multi-particle complexes of alcohols with ethers were evaluated taking into account reorganization effect.