Layered microporous titanosilicate AM-4 (Aveiro-Manchester-4) is a synthetic analog of microporous lintisite-type minerals. We applied the hydrothermal method to synthesize AM-4 compound from different titanium sources, i.e. titanium (III) chloride solution, titanyl-sulfate (titanite ore treatment product) and sodium metasilicate by stepwise cooling of an initial titanium-silicate mixture. In acid solution the crystal structure of AM-4 transformed into a novel layered titanosilicate SL3 (synthetic decationated lintisite) with a unique topology that consists of Ti₂Si₄O₁₀(OH)₄ nano-blocks. It was found that SL3 compound had a tendency for uptake of Ag from the standard test copper-nickel electrolyte. A possibility of repeated use of SL3 as a renewable sorbent was shown on the example of sorption Ca²⁺ cations. Both AM-4 and SL3 compounds can be considered as new functional materials of renewable and thermally stable nature with potential application for sorption and immobilization of the radioactive iodine isotopes.