Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
The microbiome in endometrial cancer: vaginal milieu matters. / Govorov, I; Komlichenko, E; Ulrikh, E; Dikareva, E; Pervunina, T; Vazhenina, O; Dzharbaeva, A; Kalinina, O; Zaikova, E; Razumova, Z; Mints, M; Sitkin, S.
в: Frontiers in Medicine, Том 12, 2025.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - The microbiome in endometrial cancer: vaginal milieu matters
AU - Govorov, I
AU - Komlichenko, E
AU - Ulrikh, E
AU - Dikareva, E
AU - Pervunina, T
AU - Vazhenina, O
AU - Dzharbaeva, A
AU - Kalinina, O
AU - Zaikova, E
AU - Razumova, Z
AU - Mints, M
AU - Sitkin, S
N1 - Times Cited in Web of Science Core Collection: 1 Total Times Cited: 1 Cited Reference Count: 58
PY - 2025
Y1 - 2025
N2 - Endometrial cancer remains one of the most common malignancies in women, and its incidence is particularly increasing in developed countries. Despite the well-known promotive role of excessive exposure to estrogen, many other details of the pathogenesis of endometrial cancer remain unknown. Recent studies have elucidated the emerging role of the resident microbiota in the progression of various diseases, including cancer. Next-generation sequencing demonstrated that the uterine cavity, previously considered sterile, contains a composition-rich microbiota. In this work, we determined the differences in the composition of the intrauterine microbiota between patients with endometrial cancer and its precursor-endometrial hyperplasia.
AB - Endometrial cancer remains one of the most common malignancies in women, and its incidence is particularly increasing in developed countries. Despite the well-known promotive role of excessive exposure to estrogen, many other details of the pathogenesis of endometrial cancer remain unknown. Recent studies have elucidated the emerging role of the resident microbiota in the progression of various diseases, including cancer. Next-generation sequencing demonstrated that the uterine cavity, previously considered sterile, contains a composition-rich microbiota. In this work, we determined the differences in the composition of the intrauterine microbiota between patients with endometrial cancer and its precursor-endometrial hyperplasia.
KW - endometrial cancer
KW - microbiota
KW - endometrial microbiota
KW - endometrial hyperplasia
KW - carcinogenesis
KW - vaginal microbiota
U2 - 10.3389/fmed.2025.1533344
DO - 10.3389/fmed.2025.1533344
M3 - Article
VL - 12
JO - Frontiers in Medicine
JF - Frontiers in Medicine
SN - 2296-858X
ER -
ID: 147943169