Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
The first one-pot room-temperature protocol for the synthesis of 3,5-disubstituted-1,2,4-oxadiazoles via the condensation between amidoximes and carboxylic acid esters in superbase medium MOH/DMSO is reported. A broad spectrum of alkyl, aryl and hetaryl amidoximes and esters was examined. This reaction route provides convenient access to 1,2,4-oxadiazoles, which is highly desirable because in the light of this privileged scaffold is recognized as an important core in the design of novel therapeutic agents and high-tech materials.
Язык оригинала | английский |
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Страницы (с-по) | 945-951 |
Число страниц | 7 |
Журнал | Tetrahedron |
Том | 73 |
Номер выпуска | 7 |
DOI | |
Состояние | Опубликовано - 1 янв 2017 |
ID: 35259001