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The experimental study of ' 99m Tc-ciprofloxacin' for diagnosis of bacterial infection. / Lishmanov, Yu B.; Sazonova, S. I.; Sokolovich, E. G.; Zavodovskij, K. V.; Chernov, V. I.

в: Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost', Том 47, № 4, 2002, стр. 49-54.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Lishmanov, YB, Sazonova, SI, Sokolovich, EG, Zavodovskij, KV & Chernov, VI 2002, 'The experimental study of ' 99m Tc-ciprofloxacin' for diagnosis of bacterial infection', Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost', Том. 47, № 4, стр. 49-54. <https://elibrary.ru/item.asp?id=14964599>

APA

Lishmanov, Y. B., Sazonova, S. I., Sokolovich, E. G., Zavodovskij, K. V., & Chernov, V. I. (2002). The experimental study of ' 99m Tc-ciprofloxacin' for diagnosis of bacterial infection. Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost', 47(4), 49-54. https://elibrary.ru/item.asp?id=14964599

Vancouver

Lishmanov YB, Sazonova SI, Sokolovich EG, Zavodovskij KV, Chernov VI. The experimental study of ' 99m Tc-ciprofloxacin' for diagnosis of bacterial infection. Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'. 2002;47(4):49-54.

Author

Lishmanov, Yu B. ; Sazonova, S. I. ; Sokolovich, E. G. ; Zavodovskij, K. V. ; Chernov, V. I. / The experimental study of ' 99m Tc-ciprofloxacin' for diagnosis of bacterial infection. в: Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'. 2002 ; Том 47, № 4. стр. 49-54.

BibTeX

@article{2c0f9ee9d7fa48b69928219e1165c223,
title = "The experimental study of ' 99m Tc-ciprofloxacin' for diagnosis of bacterial infection",
abstract = " Pharmacokinetic studies were performed at 120 white mice after intravenous injection of 5.3 MBq/kg 99m Tc-ciprofloxacin into the femoral venue. Blood and organs radiometry was made using gamma spectrometer 'Tracor Analytic'. Suitability of bacterial infection imaging using this radiopharmaceutical studied with two groups of laboratory animals. The first group includes 5 rabbits with abscess and the second - 5 with aseptic inflammation. Scintigrafic imaging of experimental bacterial infection in rabbits is most successful at 1.5-2 hours after intravenous injection of 99m Tc-ciprofloxacin. Pharmacokinetic studies showed the urinogenous system as main in radiopharmaceutical elimination. The biological half-elimination period of radiopharmaceutical's is 135 minutes. Summary accumulation of 99m Tc-ciprofloxacin in organs is not more than 10% of injected dose. The study shows that 99m Tc-ciprofloxacin is harmless and suitable for diagnoses of bacterial infection. ",
keywords = "Bacterial infection, Diagnosis, Pharmacokinetic, The Tc-ciprofloxacin",
author = "Lishmanov, {Yu B.} and Sazonova, {S. I.} and Sokolovich, {E. G.} and Zavodovskij, {K. V.} and Chernov, {V. I.}",
year = "2002",
language = "English",
volume = "47",
pages = "49--54",
journal = "Медицинская радиология и радиационная безопасность",
issn = "0025-8334",
publisher = "Izdatel'sto Radekon",
number = "4",

}

RIS

TY - JOUR

T1 - The experimental study of ' 99m Tc-ciprofloxacin' for diagnosis of bacterial infection

AU - Lishmanov, Yu B.

AU - Sazonova, S. I.

AU - Sokolovich, E. G.

AU - Zavodovskij, K. V.

AU - Chernov, V. I.

PY - 2002

Y1 - 2002

N2 - Pharmacokinetic studies were performed at 120 white mice after intravenous injection of 5.3 MBq/kg 99m Tc-ciprofloxacin into the femoral venue. Blood and organs radiometry was made using gamma spectrometer 'Tracor Analytic'. Suitability of bacterial infection imaging using this radiopharmaceutical studied with two groups of laboratory animals. The first group includes 5 rabbits with abscess and the second - 5 with aseptic inflammation. Scintigrafic imaging of experimental bacterial infection in rabbits is most successful at 1.5-2 hours after intravenous injection of 99m Tc-ciprofloxacin. Pharmacokinetic studies showed the urinogenous system as main in radiopharmaceutical elimination. The biological half-elimination period of radiopharmaceutical's is 135 minutes. Summary accumulation of 99m Tc-ciprofloxacin in organs is not more than 10% of injected dose. The study shows that 99m Tc-ciprofloxacin is harmless and suitable for diagnoses of bacterial infection.

AB - Pharmacokinetic studies were performed at 120 white mice after intravenous injection of 5.3 MBq/kg 99m Tc-ciprofloxacin into the femoral venue. Blood and organs radiometry was made using gamma spectrometer 'Tracor Analytic'. Suitability of bacterial infection imaging using this radiopharmaceutical studied with two groups of laboratory animals. The first group includes 5 rabbits with abscess and the second - 5 with aseptic inflammation. Scintigrafic imaging of experimental bacterial infection in rabbits is most successful at 1.5-2 hours after intravenous injection of 99m Tc-ciprofloxacin. Pharmacokinetic studies showed the urinogenous system as main in radiopharmaceutical elimination. The biological half-elimination period of radiopharmaceutical's is 135 minutes. Summary accumulation of 99m Tc-ciprofloxacin in organs is not more than 10% of injected dose. The study shows that 99m Tc-ciprofloxacin is harmless and suitable for diagnoses of bacterial infection.

KW - Bacterial infection

KW - Diagnosis

KW - Pharmacokinetic

KW - The Tc-ciprofloxacin

UR - http://www.scopus.com/inward/record.url?scp=0036414036&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0036414036

VL - 47

SP - 49

EP - 54

JO - Медицинская радиология и радиационная безопасность

JF - Медицинская радиология и радиационная безопасность

SN - 0025-8334

IS - 4

ER -

ID: 45772808